ID   Y2478_STAAM             Reviewed;         231 AA.
AC   Q99RF5;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 119.
DE   RecName: Full=Uncharacterized oxidoreductase SAV2478;
DE            EC=1.-.-.-;
GN   OrderedLocusNames=SAV2478;
OS   Staphylococcus aureus (strain Mu50 / ATCC 700699).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=158878;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Mu50 / ATCC 700699;
RX   PubMed=11418146; DOI=10.1016/s0140-6736(00)04403-2;
RA   Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L.,
RA   Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M.,
RA   Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y.,
RA   Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H.,
RA   Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K.,
RA   Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H.,
RA   Hiramatsu K.;
RT   "Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
RL   Lancet 357:1225-1240(2001).
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000305}.
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DR   EMBL; BA000017; BAB58640.1; -; Genomic_DNA.
DR   RefSeq; WP_000217456.1; NC_002758.2.
DR   AlphaFoldDB; Q99RF5; -.
DR   SMR; Q99RF5; -.
DR   World-2DPAGE; 0002:Q99RF5; -.
DR   PaxDb; Q99RF5; -.
DR   EnsemblBacteria; BAB58640; BAB58640; SAV2478.
DR   KEGG; sav:SAV2478; -.
DR   HOGENOM; CLU_010194_2_10_9; -.
DR   OMA; ITGGRNW; -.
DR   PhylomeDB; Q99RF5; -.
DR   BioCyc; SAUR158878:SAV_RS13525-MON; -.
DR   Proteomes; UP000002481; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR002347; SDR_fam.
DR   Pfam; PF00106; adh_short; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase.
FT   CHAIN           1..231
FT                   /note="Uncharacterized oxidoreductase SAV2478"
FT                   /id="PRO_0000300473"
FT   ACT_SITE        153
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000250"
FT   BINDING         10..34
FT                   /ligand="NADP(+)"
FT                   /ligand_id="ChEBI:CHEBI:58349"
FT                   /evidence="ECO:0000250"
FT   BINDING         140
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   231 AA;  24578 MW;  EED1BCE261E87778 CRC64;
     MTVLTDKIAV VTGAGSGIGE AIATLLHEEG AKVVLAGRNK DKLQNVANQL AQDSVKVVPT
     DVTNKEEVDE LMKIAQQTFG GLDIVINSAG QMLSSKITDY QVDEWDSMID VNIKGTLYTA
     QAALPTMLEQ SSGHLINIAS ISGFEVTKSS TIYSATKAAV HTITQGLEKE LAKTGVKVTS
     ISPGMVDTAI TAAYNPSDRK KLDPQDIAEA VLYALTQPKH VNVNEITVRP V