ID   Y248_MYCGE              Reviewed;         218 AA.
AC   P47490;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Putative tRNA methyltransferase MG248;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MG248;
OS   Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
OS   (Mycoplasmoides genitalium).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=243273;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=7569993; DOI=10.1126/science.270.5235.397;
RA   Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA   Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA   Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA   Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA   Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA   Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT   "The minimal gene complement of Mycoplasma genitalium.";
RL   Science 270:397-403(1995).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TrmK family. {ECO:0000305}.
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DR   EMBL; L43967; AAC71468.1; -; Genomic_DNA.
DR   PIR; D64227; D64227.
DR   RefSeq; WP_009885786.1; NZ_AAGX01000005.1.
DR   AlphaFoldDB; P47490; -.
DR   SMR; P47490; -.
DR   STRING; 243273.MG_248; -.
DR   EnsemblBacteria; AAC71468; AAC71468; MG_248.
DR   KEGG; mge:MG_248; -.
DR   eggNOG; COG2384; Bacteria.
DR   HOGENOM; CLU_071037_2_1_14; -.
DR   OMA; GTDHGYI; -.
DR   OrthoDB; 1627266at2; -.
DR   BioCyc; MGEN243273:G1GJ2-295-MON; -.
DR   Proteomes; UP000000807; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016429; F:tRNA (adenine-N1-)-methyltransferase activity; IBA:GO_Central.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR006901; TrmK.
DR   Pfam; PF04816; TrmK; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Methyltransferase; Reference proteome; S-adenosyl-L-methionine;
KW   Transferase; tRNA processing.
FT   CHAIN           1..218
FT                   /note="Putative tRNA methyltransferase MG248"
FT                   /id="PRO_0000210487"
SQ   SEQUENCE   218 AA;  25188 MW;  E213395E1B87CB7D CRC64;
     MKKRISTIAN LVQSFNPKLV YDIGCDHSYL TSYLIKTNQN LTIVNSDISK NALLSNYQKF
     KNNNNIHFFV SDGFNNLPEL NINPKIGVIA GLGGLKIINI ISQKENFINR FVIQPQSNLI
     ELRSFLSLNS WDIVNETLVQ DREFIYPILV IEKLKKPFKL TKELVILGPK LINFKDKHCL
     MKHYQCLLRV YQPKQKPSLM DLKIIETLNK IITSYESS