Y248_TREPA
ID Y248_TREPA Reviewed; 134 AA.
AC O83276;
DT 01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 23-FEB-2022, entry version 89.
DE RecName: Full=Uncharacterized lipoprotein TP_0248;
DE Flags: Precursor;
GN OrderedLocusNames=TP_0248;
OS Treponema pallidum (strain Nichols).
OC Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX NCBI_TaxID=243276;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nichols;
RX PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA Venter J.C.;
RT "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL Science 281:375-388(1998).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE000520; AAC65241.1; -; Genomic_DNA.
DR PIR; C71348; C71348.
DR RefSeq; WP_010881696.1; NC_000919.1.
DR IntAct; O83276; 2.
DR EnsemblBacteria; AAC65241; AAC65241; TP_0248.
DR KEGG; tpa:TP_0248; -.
DR HOGENOM; CLU_1895266_0_0_12; -.
DR OMA; CWTLLLM; -.
DR Proteomes; UP000000811; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW Signal.
FT SIGNAL 1..23
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT CHAIN 24..134
FT /note="Uncharacterized lipoprotein TP_0248"
FT /id="PRO_0000014244"
FT LIPID 24
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT LIPID 24
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ SEQUENCE 134 AA; 14843 MW; 75C5A52EB2E99F1F CRC64;
MWHLRCSNWR GSGVFGMCFS LSGCVMGQWC VSRAIVRGHT QGGAVREVVR ELLLGPQHHG
YARLVDPAVR PLSCFSRGDT LYIDLPVGVL SPKYRTCSLH RAYELXERSV VLNCAPVKRV
CFYVGGRAGF ESDG