ID   Y249_METTH              Reviewed;         197 AA.
AC   O26351;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 102.
DE   RecName: Full=Uncharacterized protein MTH_249;
GN   OrderedLocusNames=MTH_249;
OS   Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM
OS   10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX   NCBI_TaxID=187420;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H;
RX   PubMed=9371463; DOI=10.1128/jb.179.22.7135-7155.1997;
RA   Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J.,
RA   Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D.,
RA   Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R.,
RA   Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D.,
RA   Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A.,
RA   Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J.,
RA   Reeve J.N.;
RT   "Complete genome sequence of Methanobacterium thermoautotrophicum deltaH:
RT   functional analysis and comparative genomics.";
RL   J. Bacteriol. 179:7135-7155(1997).
CC   -!- SIMILARITY: Belongs to the SIS family. PHI subfamily. {ECO:0000305}.
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DR   EMBL; AE000666; AAB84755.1; -; Genomic_DNA.
DR   PIR; B69131; B69131.
DR   AlphaFoldDB; O26351; -.
DR   SMR; O26351; -.
DR   STRING; 187420.MTH_249; -.
DR   EnsemblBacteria; AAB84755; AAB84755; MTH_249.
DR   KEGG; mth:MTH_249; -.
DR   PATRIC; fig|187420.15.peg.218; -.
DR   HOGENOM; CLU_094236_1_0_2; -.
DR   OMA; HIFLQGA; -.
DR   Proteomes; UP000005223; Chromosome.
DR   GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR   GO; GO:0016853; F:isomerase activity; IEA:InterPro.
DR   GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR   CDD; cd05005; SIS_PHI; 1.
DR   InterPro; IPR017552; PHI/rmpB.
DR   InterPro; IPR001347; SIS_dom.
DR   InterPro; IPR046348; SIS_dom_sf.
DR   PANTHER; PTHR43443; PTHR43443; 1.
DR   Pfam; PF01380; SIS; 1.
DR   SUPFAM; SSF53697; SSF53697; 1.
DR   TIGRFAMs; TIGR03127; RuMP_HxlB; 1.
DR   PROSITE; PS51464; SIS; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..197
FT                   /note="Uncharacterized protein MTH_249"
FT                   /id="PRO_0000136571"
FT   DOMAIN          33..184
FT                   /note="SIS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00797"
SQ   SEQUENCE   197 AA;  21570 MW;  9840D27964B6F267 CRC64;
     MIEMEILRNT VQKIAKHAIE AIDKVDEAEL EMMISKIMDA SSVFIVGTGR SELIGKAFAM
     RLMHLGFKVH VVGDVTTPAI RDEDCLIAIS GSGETKTVTL AAETSRSVGA TVVAVTATPE
     STLTGYSDVV ICIPSKTKEP WKYYTSGVLR GEYDDLTPMG TLFEDSTHLF LDGLIAEFMS
     ILGKREKDLK ERHAIIE