ID   Y249_PYRAB              Reviewed;         324 AA.
AC   Q9V225; G8ZG85;
DT   29-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=Putative GTPase PYRAB02490;
DE            EC=3.6.-.-;
GN   OrderedLocusNames=PYRAB02490; ORFNames=PAB2398;
OS   Pyrococcus abyssi (strain GE5 / Orsay).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=272844;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GE5 / Orsay;
RX   PubMed=12622808; DOI=10.1046/j.1365-2958.2003.03381.x;
RA   Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O.,
RA   Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J.,
RA   Weissenbach J., Zivanovic Y., Forterre P.;
RT   "An integrated analysis of the genome of the hyperthermophilic archaeon
RT   Pyrococcus abyssi.";
RL   Mol. Microbiol. 47:1495-1512(2003).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=GE5 / Orsay;
RX   PubMed=22057919; DOI=10.1007/s00284-011-0035-x;
RA   Gao J., Wang J.;
RT   "Re-annotation of two hyperthermophilic archaea Pyrococcus abyssi GE5 and
RT   Pyrococcus furiosus DSM 3638.";
RL   Curr. Microbiol. 64:118-129(2012).
CC   -!- FUNCTION: May have GTPase activity. May also bind and hydrolyze ATP.
CC       May function as chaperone (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB
CC       subfamily. {ECO:0000305}.
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DR   EMBL; AJ248283; CAB49173.1; -; Genomic_DNA.
DR   EMBL; HE613800; CCE69626.1; -; Genomic_DNA.
DR   PIR; F75215; F75215.
DR   RefSeq; WP_010867373.1; NC_000868.1.
DR   AlphaFoldDB; Q9V225; -.
DR   SMR; Q9V225; -.
DR   STRING; 272844.PAB2398; -.
DR   PRIDE; Q9V225; -.
DR   EnsemblBacteria; CAB49173; CAB49173; PAB2398.
DR   GeneID; 1495139; -.
DR   KEGG; pab:PAB2398; -.
DR   PATRIC; fig|272844.11.peg.267; -.
DR   eggNOG; arCOG01226; Archaea.
DR   HOGENOM; CLU_043725_1_0_2; -.
DR   OMA; WMWERID; -.
DR   OrthoDB; 80898at2157; -.
DR   PhylomeDB; Q9V225; -.
DR   Proteomes; UP000000810; Chromosome.
DR   Proteomes; UP000009139; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR005129; GTPase_ArgK.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00750; lao; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; GTP-binding; Hydrolase; Nucleotide-binding.
FT   CHAIN           1..324
FT                   /note="Putative GTPase PYRAB02490"
FT                   /id="PRO_0000157823"
FT   BINDING         52..60
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   BINDING         194
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   BINDING         229..231
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   324 AA;  35694 MW;  0DDF2A86F1DC55A4 CRC64;
     MIDELIERMK KGDRRATARL ITLVENDEEK AREIIRKIYP LTGNAYIVGI TGPPGAGKST
     LLDKLIKEAR KEGLIVGVIA IDPTSPFTGG ALLGDRIRMQ RHSTDPGVFI RSMATRGSLG
     GLAKATNDAI KVLDAYGCDV IFVETVGVGQ VEVDIVKTAD TVVLVTVPGL GDDVQTIKAG
     LMEIADIFVI NKADKEGADA TYFELNLALD LESDKWRELG WRPPVVETVA TMNKGIKELW
     DKIKEHREFL ERSGRLKEKR RKRIEEEIKT IVSGIIAGKV EASIKRGEFE EIIRRVSQKD
     IDPYSAADMI LKEIIGGGLS VQEN