ID   Y2500_MYCSK             Reviewed;         335 AA.
AC   A1UFT9;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=UPF0353 protein Mkms_2500 {ECO:0000255|HAMAP-Rule:MF_01340};
GN   OrderedLocusNames=Mkms_2500;
OS   Mycobacterium sp. (strain KMS).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; unclassified Mycobacterium.
OX   NCBI_TaxID=189918;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KMS;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Miller C.D.,
RA   Richardson P.;
RT   "Complete sequence of chromosome of Mycobacterium sp. KMS.";
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01340};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01340}.
CC   -!- SIMILARITY: Belongs to the UPF0353 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01340}.
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DR   EMBL; CP000518; ABL91697.1; -; Genomic_DNA.
DR   RefSeq; WP_011559851.1; NC_008705.1.
DR   AlphaFoldDB; A1UFT9; -.
DR   SMR; A1UFT9; -.
DR   STRING; 189918.Mkms_2500; -.
DR   EnsemblBacteria; ABL91697; ABL91697; Mkms_2500.
DR   KEGG; mkm:Mkms_2500; -.
DR   HOGENOM; CLU_024570_2_0_11; -.
DR   OMA; RYFRATD; -.
DR   OrthoDB; 736429at2; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.50.410; -; 1.
DR   HAMAP; MF_01340; UPF0353; 1.
DR   InterPro; IPR024163; Aerotolerance_reg_N.
DR   InterPro; IPR022933; UPF0353.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   Pfam; PF07584; BatA; 1.
DR   Pfam; PF13519; VWA_2; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; SSF53300; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..335
FT                   /note="UPF0353 protein Mkms_2500"
FT                   /id="PRO_1000067654"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
FT   TRANSMEM        67..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
FT   TRANSMEM        309..329
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
FT   DOMAIN          98..294
FT                   /note="VWFA"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
SQ   SEQUENCE   335 AA;  35950 MW;  D88739667F9852F9 CRC64;
     MTLPLLGPMS FSGFEHPWFF LFLIVVLALA GLYVIVALAR QRRILRFANM ELLESVAPNR
     PNRWRHLPAI LLVASLVLLT VAMAGPTRDV RVPRNRAVVM LVIDVSQSMR ATDVSPSRLA
     AAQEASKQFA DELTPGINLG LIAYAGTATV LVSPTTNREA TKTAIDKLQL ADRTATGEGI
     FTALQAIATV GAVIGGGDEP PPARIVLFSD GKETVPSNPD NPKGAFTAAR TAKDQGVPIS
     TISFGTPYGY VEINEQRQPV PVDDQMLKKI ADLSEGEAFT ASSLEQLREV YANLQQQIGY
     ETIKGDASVG WLRLGALVLA LSALAALLLN RRLPG