ID   Y2503_LACPL             Reviewed;         285 AA.
AC   Q88UI3; F9UR32;
DT   13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=Putative sugar uptake protein lp_2503;
GN   OrderedLocusNames=lp_2503;
OS   Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
OS   (Lactobacillus plantarum).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lactiplantibacillus.
OX   NCBI_TaxID=220668;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-793 / NCIMB 8826 / WCFS1;
RX   PubMed=12566566; DOI=10.1073/pnas.0337704100;
RA   Kleerebezem M., Boekhorst J., van Kranenburg R., Molenaar D., Kuipers O.P.,
RA   Leer R., Tarchini R., Peters S.A., Sandbrink H.M., Fiers M.W.E.J.,
RA   Stiekema W., Klein Lankhorst R.M., Bron P.A., Hoffer S.M.,
RA   Nierop Groot M.N., Kerkhoven R., De Vries M., Ursing B., De Vos W.M.,
RA   Siezen R.J.;
RT   "Complete genome sequence of Lactobacillus plantarum WCFS1.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:1990-1995(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-793 / NCIMB 8826 / WCFS1;
RX   PubMed=22156394; DOI=10.1128/jb.06275-11;
RA   Siezen R.J., Francke C., Renckens B., Boekhorst J., Wels M.,
RA   Kleerebezem M., van Hijum S.A.;
RT   "Complete resequencing and reannotation of the Lactobacillus plantarum
RT   WCFS1 genome.";
RL   J. Bacteriol. 194:195-196(2012).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the GRP transporter (TC 2.A.7.5) family.
CC       {ECO:0000305}.
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DR   EMBL; AL935263; CCC79671.1; -; Genomic_DNA.
DR   RefSeq; WP_003642758.1; NC_004567.2.
DR   RefSeq; YP_004890185.1; NC_004567.2.
DR   AlphaFoldDB; Q88UI3; -.
DR   SMR; Q88UI3; -.
DR   STRING; 220668.lp_2503; -.
DR   DNASU; 1062677; -.
DR   EnsemblBacteria; CCC79671; CCC79671; lp_2503.
DR   GeneID; 57025935; -.
DR   KEGG; lpl:lp_2503; -.
DR   PATRIC; fig|220668.9.peg.2108; -.
DR   eggNOG; COG4975; Bacteria.
DR   HOGENOM; CLU_076024_0_0_9; -.
DR   OMA; GHEPFAK; -.
DR   PhylomeDB; Q88UI3; -.
DR   BioCyc; LPLA220668:G1GW0-2163-MON; -.
DR   Proteomes; UP000000432; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015144; F:carbohydrate transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR010651; Sugar_transport.
DR   PANTHER; PTHR16119; PTHR16119; 2.
DR   Pfam; PF06800; Sugar_transport; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Sugar transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..285
FT                   /note="Putative sugar uptake protein lp_2503"
FT                   /id="PRO_0000213653"
FT   TRANSMEM        2..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        31..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        55..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        112..134
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        147..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        179..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        209..228
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        233..255
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        264..283
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   285 AA;  30272 MW;  87E12EF6E0C7B3A0 CRC64;
     MGILIALIPA IAWGSIGLIS GRMGGTARQQ TLGMTMGALV FGLALWAVEQ PTLTSKIWLI
     GIVSGLFWSI GQGQQFTSMK AVGISRTTPI STGMQLVANA LAGVLLFNEW HGNMYWIGSA
     SVIVLIAGAV LTSLTDKTDP NRSASENWGV GIRALILSTI GYAGYTIVVH YGNVNAQAVV
     MPQAVGMLLG ALIWSFKDKP WVVKATYRNI VTGLVWGIGN LFMFMAMAQI GQAVAYSLSQ
     MGIVISTFGS IYLLGEHKTK REMVYVVIGS ILVIVGGVAL SLMKA