ID   Y2505_MYCUA             Reviewed;         995 AA.
AC   A0PR79;
DT   12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=UPF0182 protein MUL_2505 {ECO:0000255|HAMAP-Rule:MF_01600};
GN   OrderedLocusNames=MUL_2505;
OS   Mycobacterium ulcerans (strain Agy99).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=362242;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Agy99;
RX   PubMed=17210928; DOI=10.1101/gr.5942807;
RA   Stinear T.P., Seemann T., Pidot S., Frigui W., Reysset G., Garnier T.,
RA   Meurice G., Simon D., Bouchier C., Ma L., Tichit M., Porter J.L., Ryan J.,
RA   Johnson P.D.R., Davies J.K., Jenkin G.A., Small P.L.C., Jones L.M.,
RA   Tekaia F., Laval F., Daffe M., Parkhill J., Cole S.T.;
RT   "Reductive evolution and niche adaptation inferred from the genome of
RT   Mycobacterium ulcerans, the causative agent of Buruli ulcer.";
RL   Genome Res. 17:192-200(2007).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01600};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01600}.
CC   -!- SIMILARITY: Belongs to the UPF0182 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01600}.
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DR   EMBL; CP000325; ABL04848.1; -; Genomic_DNA.
DR   RefSeq; WP_011740463.1; NC_008611.1.
DR   AlphaFoldDB; A0PR79; -.
DR   SMR; A0PR79; -.
DR   STRING; 362242.MUL_2505; -.
DR   PRIDE; A0PR79; -.
DR   EnsemblBacteria; ABL04848; ABL04848; MUL_2505.
DR   KEGG; mul:MUL_2505; -.
DR   eggNOG; COG1615; Bacteria.
DR   HOGENOM; CLU_007733_1_0_11; -.
DR   OMA; HLRYPQD; -.
DR   Proteomes; UP000000765; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01600; UPF0182; 1.
DR   InterPro; IPR005372; UPF0182.
DR   PANTHER; PTHR39344; PTHR39344; 1.
DR   Pfam; PF03699; UPF0182; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..995
FT                   /note="UPF0182 protein MUL_2505"
FT                   /id="PRO_0000291285"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        113..133
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        175..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        210..230
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        259..279
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        287..307
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   REGION          900..947
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        916..940
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   995 AA;  108190 MW;  825E1084A9A344B8 CRC64;
     MGMRPTARMP KLTRRSRVLI LIALGVIALL LAGPRLIDAY VDWLWFGELG YLSVFTTVLV
     TRFLVFLVAG VLVGGIVFAG LALAYRTRPV FVPNNDNDPV ARYRTVVLAR LRLFGIGIPA
     AIGLLAGIVA QSYWVRIQLF LHGGDFGITD PQFGKDLGFY AFELPFYRLL LSYLFVAIFL
     AFVANVVSHY LFGGIRLTGR SGALSRSARI QLVSLVGVLV LLKTVAYWLN RYELLSHTRG
     GKPFTGAGYT DINAVLPAKL ILMAIAVICA AAVFSAIVLR DLRIPAIGLV LLLLSSLIVG
     AAWPMIVEQI SVKPNAAQKE SEYISRSITA TRQAYGLTSN VVTYRNYTGD GEATAQQVAA
     DRATTSNIRL LDPTIVSPAF TQFQQGKNFY YFPDQLSIDR YFDRNNNLRD YVVAARELNP
     DRLIDNQRDW INRHTVYTHG NGFIASPANT VRGIANDPNQ NGGYPEFLVN VVGANGTVVS
     DGPAPLDQPR IYYGPVISNT PADYAIVGKT GADREYDYET SADTKNYTYT GSGGVSVGSW
     ISRTVFAAKF AERNFLFSNV IGSNSKILFN RDPAQRVEAV APWLTTDSAV YPAIVNKRMV
     WILDGYTTLD NYPYSQLTSL SSATADSNEV AFNRLLPDKQ VSYIRNSVKA TVDAYDGTVT
     LYQQDEQDPV LKAWMQVFPG TVKPKGDISP ELAAHLRYPE DLFKVQRMLL AKYHVNDPVT
     FFSTSDFWDV PLDPNPTASS YQPPYYIVAK NIAKNDNSAS YQLISAMNRF KRDYLAAYIS
     ASSDPATYGK ITVLTIPGQV NGPKLANNAI TTDPAVSQDL GVIGRDNQNR IRWGNLLTLP
     VGQGGLLYVE PVYASPGASD AASSYPRLIR VAMMYNDKIG YGPTVRDALN GLFGPGAGDA
     ATGIQPTEGG APANVPPNNA PSPEALPGTP PSPPTAVPPA PEASVTLSPA RAAAMKEIQS
     AIGAARDAQK KGDFAAYGAA LQRLDDAITK FNNTQ