ID   Y2512_DICDI             Reviewed;         308 AA.
AC   Q7KWT9; Q559H9;
DT   23-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Uncharacterized protein DDB_G0272512;
DE   Flags: Precursor;
GN   ORFNames=DDB_G0272512;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
RN   [3]
RP   DEVELOPMENTAL STAGE [LARGE SCALE ANALYSIS].
RX   PubMed=12796308; DOI=10.1128/ec.2.3.627-637.2003;
RA   Maeda M., Sakamoto H., Iranfar N., Fuller D., Maruo T., Ogihara S.,
RA   Morio T., Urushihara H., Tanaka Y., Loomis W.F.;
RT   "Changing patterns of gene expression in Dictyostelium prestalk cell
RT   subtypes recognized by in situ hybridization with genes from microarray
RT   analyses.";
RL   Eukaryot. Cell 2:627-637(2003).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- DEVELOPMENTAL STAGE: Expressed in pstAO cells.
CC       {ECO:0000269|PubMed:12796308}.
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DR   EMBL; AAFI02000008; EAL71180.1; -; Genomic_DNA.
DR   RefSeq; XP_645127.1; XM_640035.1.
DR   AlphaFoldDB; Q7KWT9; -.
DR   STRING; 44689.DDB0230090; -.
DR   PaxDb; Q7KWT9; -.
DR   EnsemblProtists; EAL71180; EAL71180; DDB_G0272512.
DR   GeneID; 8618521; -.
DR   KEGG; ddi:DDB_G0272512; -.
DR   dictyBase; DDB_G0272512; -.
DR   eggNOG; ENOG502R6PV; Eukaryota.
DR   HOGENOM; CLU_904395_0_0_1; -.
DR   InParanoid; Q7KWT9; -.
DR   OMA; QCEDEST; -.
DR   PhylomeDB; Q7KWT9; -.
DR   PRO; PR:Q7KWT9; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0039706; F:co-receptor binding; IBA:GO_Central.
DR   GO; GO:0048019; F:receptor antagonist activity; IBA:GO_Central.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IBA:GO_Central.
DR   InterPro; IPR039863; DKK-like.
DR   PANTHER; PTHR12113; PTHR12113; 1.
DR   PROSITE; PS00615; C_TYPE_LECTIN_1; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..308
FT                   /note="Uncharacterized protein DDB_G0272512"
FT                   /id="PRO_0000392667"
FT   CARBOHYD        25
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        300
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   308 AA;  34534 MW;  0DDC33BB4AEE0D89 CRC64;
     MKLLLILILI INNYNLCLSY ECNSNRTYGL KGSSCEINAD CLFPEVCFNS VCSKIRTTGE
     SCTKKTDCTL TYDFGDCVNG KCEIIIATGD RCNPKVTSQK CSSSSECKNG ICQLISACNS
     YNCPLNQYCD DKTKQCKPIP NDINSIVCKA NSQCPTSHIC TSSNKCIIKY SSKVGEKCTD
     SPLQCRVFNG EICNQETQKC IKNDQYFKQC EDESTCNGGL CVCLDDVNSK SVCVGPNGEL
     NNEKCVNLEQ KLEQCLINEK CNTLSPITCK CFKQFECFQY ECNSVERFYN YKSNYYQSLN
     CSRFLTKP