ID   Y2521_LEGPH             Reviewed;          59 AA.
AC   Q5ZSJ6;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=UPF0391 membrane protein lpg2521 {ECO:0000255|HAMAP-Rule:MF_01361};
GN   OrderedLocusNames=lpg2521;
OS   Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC
OS   33152 / DSM 7513).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales;
OC   Legionellaceae; Legionella.
OX   NCBI_TaxID=272624;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Philadelphia 1 / ATCC 33152 / DSM 7513;
RX   PubMed=15448271; DOI=10.1126/science.1099776;
RA   Chien M., Morozova I., Shi S., Sheng H., Chen J., Gomez S.M., Asamani G.,
RA   Hill K., Nuara J., Feder M., Rineer J., Greenberg J.J., Steshenko V.,
RA   Park S.H., Zhao B., Teplitskaya E., Edwards J.R., Pampou S., Georghiou A.,
RA   Chou I.-C., Iannuccilli W., Ulz M.E., Kim D.H., Geringer-Sameth A.,
RA   Goldsberry C., Morozov P., Fischer S.G., Segal G., Qu X., Rzhetsky A.,
RA   Zhang P., Cayanis E., De Jong P.J., Ju J., Kalachikov S., Shuman H.A.,
RA   Russo J.J.;
RT   "The genomic sequence of the accidental pathogen Legionella pneumophila.";
RL   Science 305:1966-1968(2004).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01361};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01361}.
CC   -!- SIMILARITY: Belongs to the UPF0391 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01361}.
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DR   EMBL; AE017354; AAU28581.1; -; Genomic_DNA.
DR   RefSeq; WP_010948223.1; NC_002942.5.
DR   RefSeq; YP_096528.1; NC_002942.5.
DR   AlphaFoldDB; Q5ZSJ6; -.
DR   PaxDb; Q5ZSJ6; -.
DR   EnsemblBacteria; AAU28581; AAU28581; lpg2521.
DR   GeneID; 66491694; -.
DR   KEGG; lpn:lpg2521; -.
DR   PATRIC; fig|272624.6.peg.2679; -.
DR   eggNOG; COG5487; Bacteria.
DR   HOGENOM; CLU_187346_1_0_6; -.
DR   OMA; LRWTVIF; -.
DR   Proteomes; UP000000609; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01361; UPF0391; 1.
DR   InterPro; IPR009760; DUF1328.
DR   Pfam; PF07043; DUF1328; 1.
DR   PIRSF; PIRSF036466; UCP036466; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..59
FT                   /note="UPF0391 membrane protein lpg2521"
FT                   /id="PRO_0000256746"
FT   TRANSMEM        5..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01361"
FT   TRANSMEM        30..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01361"
SQ   SEQUENCE   59 AA;  6285 MW;  87E088FBF6700299 CRC64;
     MLSWALIFFI IAIIAAAFGF GGIAVAAAGI AKILFFLFLV MFVIFLIMGL LGRRGPPPV