ID   Y2523_STAAM             Reviewed;         223 AA.
AC   Q99RB2;
DT   06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Putative NAD(P)H nitroreductase SAV2523;
DE            EC=1.-.-.-;
GN   OrderedLocusNames=SAV2523;
OS   Staphylococcus aureus (strain Mu50 / ATCC 700699).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=158878;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Mu50 / ATCC 700699;
RX   PubMed=11418146; DOI=10.1016/s0140-6736(00)04403-2;
RA   Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L.,
RA   Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M.,
RA   Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y.,
RA   Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H.,
RA   Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K.,
RA   Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H.,
RA   Hiramatsu K.;
RT   "Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
RL   Lancet 357:1225-1240(2001).
CC   -!- COFACTOR:
CC       Name=FMN; Xref=ChEBI:CHEBI:58210; Evidence={ECO:0000305};
CC   -!- SIMILARITY: Belongs to the nitroreductase family. {ECO:0000305}.
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DR   EMBL; BA000017; BAB58685.1; -; Genomic_DNA.
DR   RefSeq; WP_000069098.1; NC_002758.2.
DR   AlphaFoldDB; Q99RB2; -.
DR   SMR; Q99RB2; -.
DR   World-2DPAGE; 0002:Q99RB2; -.
DR   PaxDb; Q99RB2; -.
DR   EnsemblBacteria; BAB58685; BAB58685; SAV2523.
DR   KEGG; sav:SAV2523; -.
DR   HOGENOM; CLU_070764_4_1_9; -.
DR   OMA; PWHFVVA; -.
DR   PhylomeDB; Q99RB2; -.
DR   BioCyc; SAUR158878:SAV_RS13765-MON; -.
DR   Proteomes; UP000002481; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   CDD; cd02149; NfsB-like; 1.
DR   Gene3D; 3.40.109.10; -; 1.
DR   InterPro; IPR033878; NfsB-like.
DR   InterPro; IPR029479; Nitroreductase.
DR   InterPro; IPR000415; Nitroreductase-like.
DR   Pfam; PF00881; Nitroreductase; 1.
DR   SUPFAM; SSF55469; SSF55469; 1.
PE   3: Inferred from homology;
KW   Flavoprotein; FMN; NAD; NADP; Oxidoreductase.
FT   CHAIN           1..223
FT                   /note="Putative NAD(P)H nitroreductase SAV2523"
FT                   /id="PRO_0000277534"
SQ   SEQUENCE   223 AA;  25375 MW;  86CFC18027E2FCB6 CRC64;
     MSNMNQTIMD AFHFRHATKQ FDPQKKVSKE DFETILESGR LSPSSLGLEP WKFVVIQDQA
     LRDELKAHSW GAAKQLDTAS HFVLIFARKN VTSRSPYVQH MLRDIKKYEA QTIPAVEQKF
     DAFQADFHIS DNDQALYDWS SKQTYIALGN MMTTAALLGI DSCPMEGFSL DTVTDILANK
     GILDTEQFGL SVMVAFGYRQ QDPPKNKTRQ AYEDVIEWVG PKE