ID   Y253_METJA              Reviewed;         154 AA.
AC   Q57701;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=Putative hydrogenase maturation protease MJ0253;
DE            EC=3.4.23.-;
GN   OrderedLocusNames=MJ0253;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- SIMILARITY: Belongs to the peptidase A31 family. {ECO:0000305}.
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DR   EMBL; L77117; AAB98240.1; -; Genomic_DNA.
DR   PIR; F64331; F64331.
DR   RefSeq; WP_010869751.1; NC_000909.1.
DR   AlphaFoldDB; Q57701; -.
DR   SMR; Q57701; -.
DR   STRING; 243232.MJ_0253; -.
DR   EnsemblBacteria; AAB98240; AAB98240; MJ_0253.
DR   GeneID; 1451107; -.
DR   KEGG; mja:MJ_0253; -.
DR   eggNOG; arCOG04429; Archaea.
DR   HOGENOM; CLU_099037_0_2_2; -.
DR   InParanoid; Q57701; -.
DR   OMA; GCGNLIF; -.
DR   OrthoDB; 122958at2157; -.
DR   PhylomeDB; Q57701; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004175; F:endopeptidase activity; IBA:GO_Central.
DR   GO; GO:0008047; F:enzyme activator activity; IEA:InterPro.
DR   GO; GO:0036211; P:protein modification process; IBA:GO_Central.
DR   GO; GO:0016485; P:protein processing; IBA:GO_Central.
DR   CDD; cd06064; H2MP_F420-Reduc; 1.
DR   Gene3D; 3.40.50.1450; -; 1.
DR   InterPro; IPR004411; Pept_A31_F420-red_hyd_d.
DR   InterPro; IPR023430; Pept_HybD-like_dom_sf.
DR   InterPro; IPR000671; Peptidase_A31.
DR   PANTHER; PTHR30302; PTHR30302; 1.
DR   Pfam; PF01750; HycI; 1.
DR   PRINTS; PR00446; HYDRGNUPTAKE.
DR   SUPFAM; SSF53163; SSF53163; 1.
DR   TIGRFAMs; TIGR00130; frhD; 1.
DR   TIGRFAMs; TIGR00072; hydrog_prot; 1.
PE   3: Inferred from homology;
KW   Aspartyl protease; Hydrolase; Protease; Reference proteome.
FT   CHAIN           1..154
FT                   /note="Putative hydrogenase maturation protease MJ0253"
FT                   /id="PRO_0000201948"
SQ   SEQUENCE   154 AA;  16846 MW;  DE03F82A1C91B365 CRC64;
     MKKKDILIVG CGNLLFGDDG FGCEVVSKLE KMNLPDNVEV IDAGASGAYY LMTLVDEDIK
     KIIVVDAIDF DLEPGTIKKI DVDELPNIKK YSFDAHNVPL APFLKDLHNK GIEVVVIGCQ
     GKEFTMPDIK PGLSEEVAKA VDKAIEIILG EIKK