ID   Y254_YERPN              Reviewed;         294 AA.
AC   Q1CN43; C4GPN3;
DT   09-FEB-2010, integrated into UniProtKB/Swiss-Prot.
DT   09-FEB-2010, sequence version 2.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=UPF0761 membrane protein YPN_0254 {ECO:0000255|HAMAP-Rule:MF_00672};
GN   OrderedLocusNames=YPN_0254; ORFNames=YP516_0245;
OS   Yersinia pestis bv. Antiqua (strain Nepal516).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=377628;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nepal516;
RX   PubMed=16740952; DOI=10.1128/jb.00124-06;
RA   Chain P.S.G., Hu P., Malfatti S.A., Radnedge L., Larimer F., Vergez L.M.,
RA   Worsham P., Chu M.C., Andersen G.L.;
RT   "Complete genome sequence of Yersinia pestis strains Antiqua and Nepal516:
RT   evidence of gene reduction in an emerging pathogen.";
RL   J. Bacteriol. 188:4453-4463(2006).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nepal516;
RA   Plunkett G. III, Anderson B.D., Baumler D.J., Burland V., Cabot E.L.,
RA   Glasner J.D., Mau B., Neeno-Eckwall E., Perna N.T., Munk A.C., Tapia R.,
RA   Green L.D., Rogers Y.C., Detter J.C., Bruce D.C., Brettin T.S.;
RT   "Yersinia pestis Nepal516A whole genome shotgun sequencing project.";
RL   Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_00672}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_00672}.
CC   -!- SIMILARITY: Belongs to the UPF0761 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00672}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABG16587.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000305; ABG16587.1; ALT_INIT; Genomic_DNA.
DR   EMBL; ACNQ01000006; EEO78033.1; -; Genomic_DNA.
DR   RefSeq; WP_002209010.1; NZ_ACNQ01000006.1.
DR   AlphaFoldDB; Q1CN43; -.
DR   EnsemblBacteria; ABG16587; ABG16587; YPN_0254.
DR   GeneID; 57974562; -.
DR   KEGG; ypn:YPN_0254; -.
DR   HOGENOM; CLU_032288_0_0_6; -.
DR   Proteomes; UP000008936; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00672; UPF0761; 1.
DR   InterPro; IPR023679; UPF0761_bac.
DR   InterPro; IPR017039; Virul_fac_BrkB.
DR   PANTHER; PTHR30213; PTHR30213; 1.
DR   Pfam; PF03631; Virul_fac_BrkB; 1.
DR   PIRSF; PIRSF035875; RNase_BN; 1.
DR   TIGRFAMs; TIGR00765; yihY_not_rbn; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..294
FT                   /note="UPF0761 membrane protein YPN_0254"
FT                   /id="PRO_0000391066"
FT   TRANSMEM        44..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
FT   TRANSMEM        67..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
FT   TRANSMEM        108..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
FT   TRANSMEM        136..156
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
FT   TRANSMEM        185..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
FT   TRANSMEM        212..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
FT   TRANSMEM        246..266
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
SQ   SEQUENCE   294 AA;  33090 MW;  5BB9E0FC38CEAE96 CRC64;
     MASFRRFRLL SPLKPCVTFG RMLYTRIDKD GLTMLAGHLA YVSLLSLVPL ITVIFALFAA
     FPMFAEISIK LKAFIFANFM PATGDIIQNY LEQFVANSNR MTVVGTCGLI VTALLLIYSV
     DSVLNIIWRS KIQRSLVFSF AVYWMVLTLG PILVGASMVI SSYLLSLHWL AHARVDSMID
     EILRVFPLLI SWVSFWLLYS VVPTVRVPAR DALIGALVAA LLFELGKKGF AMYITLFPSY
     QLIYGVLAVI PILFLWVYWS WCIVLLGAEI TVTLGEYRAE RHHAKSVTTQ SPEM