ID   Y2569_MYCTU             Reviewed;         314 AA.
AC   P9WL93; L0TA23; P0A5G5; Q50652;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 35.
DE   RecName: Full=Uncharacterized protein Rv2569c;
GN   OrderedLocusNames=Rv2569c; ORFNames=MTCY227.32;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, CLEAVAGE OF INITIATOR
RP   METHIONINE [LARGE SCALE ANALYSIS], AND IDENTIFICATION BY MASS SPECTROMETRY
RP   [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC   -!- SIMILARITY: To M.leprae ML0607. {ECO:0000305}.
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DR   EMBL; AL123456; CCP45365.1; -; Genomic_DNA.
DR   PIR; H70723; H70723.
DR   RefSeq; NP_217085.1; NC_000962.3.
DR   RefSeq; WP_003413334.1; NZ_NVQJ01000023.1.
DR   AlphaFoldDB; P9WL93; -.
DR   SMR; P9WL93; -.
DR   STRING; 83332.Rv2569c; -.
DR   iPTMnet; P9WL93; -.
DR   PaxDb; P9WL93; -.
DR   DNASU; 887783; -.
DR   GeneID; 45426571; -.
DR   GeneID; 887783; -.
DR   KEGG; mtu:Rv2569c; -.
DR   PATRIC; fig|83332.111.peg.2871; -.
DR   TubercuList; Rv2569c; -.
DR   eggNOG; COG1305; Bacteria.
DR   OMA; WGRDFSD; -.
DR   PhylomeDB; P9WL93; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; HDA:MTBBASE.
DR   InterPro; IPR013589; Bac_transglu_N.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR002931; Transglutaminase-like.
DR   Pfam; PF08379; Bact_transglu_N; 1.
DR   Pfam; PF01841; Transglut_core; 1.
DR   SMART; SM00460; TGc; 1.
DR   SUPFAM; SSF54001; SSF54001; 1.
PE   1: Evidence at protein level;
KW   Acetylation; Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0007744|PubMed:21969609"
FT   CHAIN           2..314
FT                   /note="Uncharacterized protein Rv2569c"
FT                   /id="PRO_0000104047"
FT   MOD_RES         2
FT                   /note="N-acetylserine"
FT                   /evidence="ECO:0007744|PubMed:21969609"
SQ   SEQUENCE   314 AA;  34397 MW;  47FC3EE5DC9EE09E CRC64;
     MSADSSLSLP LSGTHRYRVT HRTEYRYSDV VTSSYGRGFL TPRNSLRQRC VAHRLTIDPA
     PADRSTSRDG YGNISSYFHV TEPHRTLTIT SDSIVDVSPP PPGLYTSGPA LQPWEAARPA
     GLPGSLATEF TLDLNPPEIT DAVREYAAPS FLPKRPLVEV LRDLASRIYT DFTYRSGSTT
     ISTGVNEVLL AREGVCQDFA RLAIACLRAN GLAACYVSGY LATDPPPGKD RMIGIDATHA
     WASVWTPQQP GRFEWLGLDP TNDQLVDQRY IVVGRGRDYA DVPPLRGIIY TNSENSVIDV
     SVDVVPFEGD ALHA