ID   Y256_MYCPA              Reviewed;         314 AA.
AC   Q745R0;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase MAP_0256;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MAP_0256;
OS   Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)
OS   (Mycobacterium paratuberculosis).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=262316;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-968 / K-10;
RX   PubMed=16116077; DOI=10.1073/pnas.0505662102;
RA   Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D., Banerji N.,
RA   Kanjilal S., Kapur V.;
RT   "The complete genome sequence of Mycobacterium avium subspecies
RT   paratuberculosis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005).
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; AE016958; AAS02573.1; -; Genomic_DNA.
DR   RefSeq; WP_003873400.1; NC_002944.2.
DR   AlphaFoldDB; Q745R0; -.
DR   SMR; Q745R0; -.
DR   STRING; 262316.MAP_0256; -.
DR   EnsemblBacteria; AAS02573; AAS02573; MAP_0256.
DR   KEGG; mpa:MAP_0256; -.
DR   PATRIC; fig|262316.17.peg.270; -.
DR   eggNOG; COG3315; Bacteria.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; DSMPPTL; -.
DR   Proteomes; UP000000580; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; Reference proteome; S-adenosyl-L-methionine;
KW   Transferase.
FT   CHAIN           1..314
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase MAP_0256"
FT                   /id="PRO_0000361178"
FT   BINDING         132
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         161..162
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   314 AA;  34860 MW;  DBFF56249C3E2A62 CRC64;
     MPRTDNDSWD ITQSVGATAL GVAAARAAET ESENPLISDP FARIFVEAAG KGMWSIYADP
     ALLTKADDLE PDLRGRLQLM IDFMATRTAF FDEFFLAAAD AGVRQVVILA AGLDARSWRL
     PWPDGTVVYE LDQPKVLDFK STTLREHGAQ PKAELVNVPI DLRQDWPKAL QEAGFDASRP
     AVWSAEGLVR YLPAQAQDLL FERIDALSAP GSRLASNVPD SGFTDPDRLA RQREDMRRMR
     AAAAKLVDAE ITDFDDLWYP EERTPVDSWL RERGWDVSTA TFAELMARYG RSIPQGAQDS
     MPPTLYVSAR RRAG