ID   Y2570_STAAS             Reviewed;         184 AA.
AC   Q6G5Z0;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=UPF0397 protein SAS2570 {ECO:0000255|HAMAP-Rule:MF_01572};
GN   OrderedLocusNames=SAS2570;
OS   Staphylococcus aureus (strain MSSA476).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=282459;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MSSA476;
RX   PubMed=15213324; DOI=10.1073/pnas.0402521101;
RA   Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J.,
RA   Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A.,
RA   Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C.,
RA   Clark L., Corton C., Cronin A., Doggett J., Dowd L., Feltwell T., Hance Z.,
RA   Harris B., Hauser H., Holroyd S., Jagels K., James K.D., Lennard N.,
RA   Line A., Mayes R., Moule S., Mungall K., Ormond D., Quail M.A.,
RA   Rabbinowitsch E., Rutherford K.M., Sanders M., Sharp S., Simmonds M.,
RA   Stevens K., Whitehead S., Barrell B.G., Spratt B.G., Parkhill J.;
RT   "Complete genomes of two clinical Staphylococcus aureus strains: evidence
RT   for the rapid evolution of virulence and drug resistance.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01572};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01572}.
CC   -!- SIMILARITY: Belongs to the UPF0397 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01572}.
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DR   EMBL; BX571857; CAG44387.1; -; Genomic_DNA.
DR   RefSeq; WP_000743714.1; NC_002953.3.
DR   AlphaFoldDB; Q6G5Z0; -.
DR   KEGG; sas:SAS2570; -.
DR   HOGENOM; CLU_120023_0_0_9; -.
DR   OMA; WWSWVIA; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01572; UPF0397; 1.
DR   InterPro; IPR009825; ECF_substrate-spec-like.
DR   InterPro; IPR022914; UPF0397.
DR   Pfam; PF07155; ECF-ribofla_trS; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..184
FT                   /note="UPF0397 protein SAS2570"
FT                   /id="PRO_0000260808"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01572"
FT   TRANSMEM        44..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01572"
FT   TRANSMEM        77..97
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01572"
FT   TRANSMEM        111..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01572"
FT   TRANSMEM        148..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01572"
SQ   SEQUENCE   184 AA;  19854 MW;  7BF96FD9AC2ACD2B CRC64;
     MKKQDISVKT VVAIGIGAAV FVILGRFVVI PTGFPNTNIE TSYAFLALIS AIFGPFAGLM
     TGLVGHAIKD FTTYGSAWWS WVICSGIIGC LYGWIGLKLN LSSGRFSRKS MIYFNIGQII
     ANIICWALIA PTLDILIYNE PANKVYTQGV ISAVLNIISV GIIGTILLKA YASSQIKKGS
     LRKE