Y2584_MYCLE
ID Y2584_MYCLE Reviewed; 269 AA.
AC O69492;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 03-AUG-2022, entry version 98.
DE RecName: Full=Uncharacterized methyltransferase ML2584;
DE EC=2.1.1.-;
GN OrderedLocusNames=ML2584; ORFNames=MLCB1883.02c;
OS Mycobacterium leprae (strain TN).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=272631;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TN;
RX PubMed=11234002; DOI=10.1038/35059006;
RA Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA Barrell B.G.;
RT "Massive gene decay in the leprosy bacillus.";
RL Nature 409:1007-1011(2001).
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC {ECO:0000305}.
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DR EMBL; AL022486; CAA18551.1; -; Genomic_DNA.
DR EMBL; AL583926; CAC32116.1; -; Genomic_DNA.
DR PIR; T44866; T44866.
DR RefSeq; NP_302653.1; NC_002677.1.
DR RefSeq; WP_010908972.1; NC_002677.1.
DR AlphaFoldDB; O69492; -.
DR SMR; O69492; -.
DR STRING; 272631.ML2584; -.
DR EnsemblBacteria; CAC32116; CAC32116; CAC32116.
DR KEGG; mle:ML2584; -.
DR PATRIC; fig|272631.5.peg.4967; -.
DR Leproma; ML2584; -.
DR eggNOG; COG0500; Bacteria.
DR HOGENOM; CLU_073035_0_0_11; -.
DR OMA; TNWLSPW; -.
DR Proteomes; UP000000806; Chromosome.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; -; 1.
DR InterPro; IPR013216; Methyltransf_11.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR Pfam; PF08241; Methyltransf_11; 1.
DR SUPFAM; SSF53335; SSF53335; 1.
PE 3: Inferred from homology;
KW Methyltransferase; Reference proteome; Transferase.
FT CHAIN 1..269
FT /note="Uncharacterized methyltransferase ML2584"
FT /id="PRO_0000380601"
SQ SEQUENCE 269 AA; 29345 MW; B404F947C64617A6 CRC64;
MDTRRRVWPV AIITPHVTDV FAQRATLTRS LQLLSEFRYE QPYPARFYRA LAADTVAMVG
DLWLSTHGAP PVGRILLDVG SGSGYFAAAF ADAGVRYIGV EPDPREMHAA GPALVPKAGA
FVRASGMALP FADDAVDICL SSNVAEHVPQ PWQLGNEMLR VTKPGGLVVL SYTIWLGPFG
GHEMGLTHYL GGARAATRYV RKHGHRAKND YGSSLFPVSA ADGLNWAAST GVAVAAFPRY
HPRWAWWLTS VPVLREFVVS NLVLVLRPR