ID   Y258_HAEIN              Reviewed;         330 AA.
AC   P43974; P44597; P71347;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 2.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Putative glycosyltransferase HI_0258;
DE            EC=2.-.-.-;
GN   OrderedLocusNames=HI_0258;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
RN   [2]
RP   SEQUENCE REVISION.
RA   White O., Clayton R.A., Kerlavage A.R., Fleischmann R.D.;
RL   Submitted (SEP-1996) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 8 family. {ECO:0000305}.
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DR   EMBL; L42023; AAC21924.1; -; Genomic_DNA.
DR   PIR; C64146; C64146.
DR   RefSeq; NP_438427.1; NC_000907.1.
DR   RefSeq; WP_010868968.1; NC_000907.1.
DR   AlphaFoldDB; P43974; -.
DR   SMR; P43974; -.
DR   STRING; 71421.HI_0258; -.
DR   CAZy; GT8; Glycosyltransferase Family 8.
DR   EnsemblBacteria; AAC21924; AAC21924; HI_0258.
DR   KEGG; hin:HI_0258; -.
DR   PATRIC; fig|71421.8.peg.273; -.
DR   eggNOG; COG1442; Bacteria.
DR   HOGENOM; CLU_050833_0_2_6; -.
DR   OMA; HFTGHDK; -.
DR   PhylomeDB; P43974; -.
DR   BioCyc; HINF71421:G1GJ1-273-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR002495; Glyco_trans_8.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   Pfam; PF01501; Glyco_transf_8; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   3: Inferred from homology;
KW   Glycosyltransferase; Manganese; Metal-binding; Reference proteome;
KW   Transferase.
FT   CHAIN           1..330
FT                   /note="Putative glycosyltransferase HI_0258"
FT                   /id="PRO_0000206068"
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..30
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         44..49
FT                   /ligand="UDP"
FT                   /ligand_id="ChEBI:CHEBI:58223"
FT                   /evidence="ECO:0000250|UniProtKB:A0A0H2URJ6"
FT   BINDING         140..141
FT                   /ligand="UDP"
FT                   /ligand_id="ChEBI:CHEBI:58223"
FT                   /evidence="ECO:0000250|UniProtKB:A0A0H2URJ6"
FT   BINDING         140
FT                   /ligand="Mn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29035"
FT                   /evidence="ECO:0000250|UniProtKB:A0A0H2URJ6"
FT   BINDING         142
FT                   /ligand="Mn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29035"
FT                   /evidence="ECO:0000250|UniProtKB:A0A0H2URJ6"
FT   BINDING         270..276
FT                   /ligand="UDP"
FT                   /ligand_id="ChEBI:CHEBI:58223"
FT                   /evidence="ECO:0000250|UniProtKB:A0A0H2URJ6"
FT   BINDING         270
FT                   /ligand="Mn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29035"
FT                   /evidence="ECO:0000250|UniProtKB:A0A0H2URJ6"
SQ   SEQUENCE   330 AA;  39073 MW;  C5A6CA0207F24F9A CRC64;
     MTDRQTDRQT DRQTDRQTDR QTDRQTDRQT DGRTVSQTMN IIFSSDHYYA PYLAVSIFSI
     IKNTPKKINF YILDMKINQE NKTIINNLAS AYSCKVFFLP VCESDFQNFP KTIDYISLAT
     YARLNLTKYI KNIEKAIYID VDTLTNSSLQ ELWNIDITNY YLAACRDTFI DVKNEAYKKT
     IGLEGYSYFN AGILLINLNK WKEENIFQKS INWMNKYNNV MKYQDQDILN GICKGKVKFI
     NNRFNFTPTD RDLIKKKNLL CVKMPIVISH YCGPNKFWHK KCSHLNCHIG NLLLKEMDKI
     IDIPSSWYDH FEKIPFLIKI KRLRKRIKDN