ID   Y2590_MYCBO             Reviewed;         325 AA.
AC   P59983; A0A1R3Y1Z4; X2BL32;
DT   31-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2003, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Uncharacterized protein Mb2590;
GN   OrderedLocusNames=BQ2027_MB2590;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: To M.tuberculosis Rv2560. {ECO:0000305}.
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DR   EMBL; LT708304; SIU01208.1; -; Genomic_DNA.
DR   RefSeq; NP_856236.1; NC_002945.3.
DR   RefSeq; WP_003899377.1; NC_002945.4.
DR   AlphaFoldDB; P59983; -.
DR   EnsemblBacteria; SIU01208; SIU01208; BQ2027_MB2590.
DR   GeneID; 45426563; -.
DR   PATRIC; fig|233413.5.peg.2848; -.
DR   OMA; GEAFGWA; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   4: Predicted;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..325
FT                   /note="Uncharacterized protein Mb2590"
FT                   /id="PRO_0000104040"
FT   TRANSMEM        96..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        153..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        205..225
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        273..293
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..75
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        26..72
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   325 AA;  33138 MW;  439CE13C356D398B CRC64;
     MSQPPEHPGN PADPQGGNQG AGSYPPPGYG APPPPPGYGP PPGTYLPPGY NAPPPPPGYG
     PPPGPPPPGY PTHLQSSGFS VGDAISWSWN RFTQNAVTLV VPVLAYAVAL AAVIGATAGL
     VVALSDRATT AYTNTSGVSS ESVDITMTPA AGIVMFLGYI ALFALVLYMH AGILTGCLDI
     ADGKPVTIAT FFRPRNLGLV LVTGLLIVAL TFIGGLLCVI PGLIFGFVAQ FAVAFAVDRS
     TSPIDSVKAS IETVGSNIGG SVLSWLAQLT AVLVGELLCF VGMLIGIPVA ALIHVYTYRK
     LSGGQVVEAV RPAPPVGWPP GPQLA