Y2593_MYCBO
ID Y2593_MYCBO Reviewed; 330 AA.
AC P63402; A0A1R3Y1J9; Q50734; X2BKU1;
DT 11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=Uncharacterized ABC transporter ATP-binding protein Mb2593;
GN OrderedLocusNames=BQ2027_MB2593;
OS Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=233413;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-935 / AF2122/97;
RX PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT "The complete genome sequence of Mycobacterium bovis.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC STRAIN=ATCC BAA-935 / AF2122/97;
RX PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA Robbe-Austerman S., Gordon S.V.;
RT "Updated reference genome sequence and annotation of Mycobacterium bovis
RT AF2122/97.";
RL Genome Announc. 5:E00157-E00157(2017).
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR EMBL; LT708304; SIU01211.1; -; Genomic_DNA.
DR RefSeq; NP_856239.1; NC_002945.3.
DR RefSeq; WP_003899378.1; NC_002945.4.
DR AlphaFoldDB; P63402; -.
DR SMR; P63402; -.
DR EnsemblBacteria; SIU01211; SIU01211; BQ2027_MB2593.
DR PATRIC; fig|233413.5.peg.2852; -.
DR OMA; TERVLFM; -.
DR Proteomes; UP000001419; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR CDD; cd03255; ABC_MJ0796_LolCDE_FtsE; 1.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 2.60.120.10; -; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR018490; cNMP-bd-like.
DR InterPro; IPR018488; cNMP-bd_CS.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR017911; MacB_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; SSF51206; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR PROSITE; PS00889; CNMP_BINDING_2; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 3: Inferred from homology;
KW ATP-binding; Nucleotide-binding; Transport.
FT CHAIN 1..330
FT /note="Uncharacterized ABC transporter ATP-binding protein
FT Mb2593"
FT /id="PRO_0000093269"
FT DOMAIN 4..242
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 40..47
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 210..330
FT /ligand="a nucleoside 3',5'-cyclic phosphate"
FT /ligand_id="ChEBI:CHEBI:58464"
SQ SEQUENCE 330 AA; 35429 MW; 47A3CD3777084FB0 CRC64;
MGGLTISDLV VEYSSGGYAV RPIDGLSLDV APGSLVILLG PSGCGKTTLL SCLGGILRPK
SGSIKFDDVD ITTLEGAALA KYRRDKVGIV FQAFNLVSSL TALENVMVPL RAAGVSRAAA
RKRAEDLLIR VNLGERMKHR PGDMSGGQQQ RVAVARAIAL DPQLILADEP TAHLDFIQVE
EVLRLIRSLA QGDRVVVVAT HDSRMLPLAD RVLELMPAQV SPNQPPETVH VKAGEVLFEQ
STMGDLIYVV SEGEFEIVRE LADGGEELVK TAAPGDYFGE IGVLFHLPRS ATVRARSDAT
AVGYTAQAFR ERLGVTRVAD LIEHRELASE