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Y2593_MYCBO
ID   Y2593_MYCBO             Reviewed;         330 AA.
AC   P63402; A0A1R3Y1J9; Q50734; X2BKU1;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Uncharacterized ABC transporter ATP-binding protein Mb2593;
GN   OrderedLocusNames=BQ2027_MB2593;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR   EMBL; LT708304; SIU01211.1; -; Genomic_DNA.
DR   RefSeq; NP_856239.1; NC_002945.3.
DR   RefSeq; WP_003899378.1; NC_002945.4.
DR   AlphaFoldDB; P63402; -.
DR   SMR; P63402; -.
DR   EnsemblBacteria; SIU01211; SIU01211; BQ2027_MB2593.
DR   PATRIC; fig|233413.5.peg.2852; -.
DR   OMA; TERVLFM; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   CDD; cd03255; ABC_MJ0796_LolCDE_FtsE; 1.
DR   CDD; cd00038; CAP_ED; 1.
DR   Gene3D; 2.60.120.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR018490; cNMP-bd-like.
DR   InterPro; IPR018488; cNMP-bd_CS.
DR   InterPro; IPR000595; cNMP-bd_dom.
DR   InterPro; IPR017911; MacB_ATP-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   Pfam; PF00005; ABC_tran; 1.
DR   Pfam; PF00027; cNMP_binding; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00100; cNMP; 1.
DR   SUPFAM; SSF51206; SSF51206; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR   PROSITE; PS00889; CNMP_BINDING_2; 1.
DR   PROSITE; PS50042; CNMP_BINDING_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Nucleotide-binding; Transport.
FT   CHAIN           1..330
FT                   /note="Uncharacterized ABC transporter ATP-binding protein
FT                   Mb2593"
FT                   /id="PRO_0000093269"
FT   DOMAIN          4..242
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         40..47
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         210..330
FT                   /ligand="a nucleoside 3',5'-cyclic phosphate"
FT                   /ligand_id="ChEBI:CHEBI:58464"
SQ   SEQUENCE   330 AA;  35429 MW;  47A3CD3777084FB0 CRC64;
     MGGLTISDLV VEYSSGGYAV RPIDGLSLDV APGSLVILLG PSGCGKTTLL SCLGGILRPK
     SGSIKFDDVD ITTLEGAALA KYRRDKVGIV FQAFNLVSSL TALENVMVPL RAAGVSRAAA
     RKRAEDLLIR VNLGERMKHR PGDMSGGQQQ RVAVARAIAL DPQLILADEP TAHLDFIQVE
     EVLRLIRSLA QGDRVVVVAT HDSRMLPLAD RVLELMPAQV SPNQPPETVH VKAGEVLFEQ
     STMGDLIYVV SEGEFEIVRE LADGGEELVK TAAPGDYFGE IGVLFHLPRS ATVRARSDAT
     AVGYTAQAFR ERLGVTRVAD LIEHRELASE
 
 
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