Y2593_STAAC
ID Y2593_STAAC Reviewed; 185 AA.
AC Q5HCX3;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 15-FEB-2005, sequence version 1.
DT 25-MAY-2022, entry version 100.
DE RecName: Full=HTH-type transcriptional regulator SACOL2593;
GN OrderedLocusNames=SACOL2593;
OS Staphylococcus aureus (strain COL).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=93062;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=COL;
RX PubMed=15774886; DOI=10.1128/jb.187.7.2426-2438.2005;
RA Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J.,
RA Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J.,
RA Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H.,
RA Vamathevan J.J., Khouri H., Utterback T.R., Lee C., Dimitrov G., Jiang L.,
RA Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E.,
RA Fraser C.M.;
RT "Insights on evolution of virulence and resistance from the complete genome
RT analysis of an early methicillin-resistant Staphylococcus aureus strain and
RT a biofilm-producing methicillin-resistant Staphylococcus epidermidis
RT strain.";
RL J. Bacteriol. 187:2426-2438(2005).
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DR EMBL; CP000046; AAW38594.1; -; Genomic_DNA.
DR RefSeq; WP_001224188.1; NC_002951.2.
DR AlphaFoldDB; Q5HCX3; -.
DR SMR; Q5HCX3; -.
DR EnsemblBacteria; AAW38594; AAW38594; SACOL2593.
DR KEGG; sac:SACOL2593; -.
DR HOGENOM; CLU_069356_17_2_9; -.
DR OMA; DAIENRQ; -.
DR Proteomes; UP000000530; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR InterPro; IPR023772; DNA-bd_HTH_TetR-type_CS.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS01081; HTH_TETR_1; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding; Transcription; Transcription regulation.
FT CHAIN 1..185
FT /note="HTH-type transcriptional regulator SACOL2593"
FT /id="PRO_0000286690"
FT DOMAIN 6..66
FT /note="HTH tetR-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00335"
FT DNA_BIND 29..48
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 185 AA; 22260 MW; B61F5B984ECAD14F CRC64;
MRKDAKENRQ RIEEIAHKLF DEEGVENISM NRIAKELGIG MGTLYRHFKD KSDLCYYVIQ
RDLDIFITHF KQIKDDYHSN YEVMQVSLDY LLQFKIDNKA LLQCIEAGNN KLRFYQSAFY
QELFDFYYDL FKSDDDTYTK FKTDMLLQSL STSVFAFQIE HRHISIEAYR NYLLNIYLDE
VGRND