ID   Y2594_LACPL             Reviewed;         282 AA.
AC   Q88UB3; F9URA2;
DT   13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Putative sugar uptake protein lp_2594;
GN   OrderedLocusNames=lp_2594;
OS   Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
OS   (Lactobacillus plantarum).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lactiplantibacillus.
OX   NCBI_TaxID=220668;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-793 / NCIMB 8826 / WCFS1;
RX   PubMed=12566566; DOI=10.1073/pnas.0337704100;
RA   Kleerebezem M., Boekhorst J., van Kranenburg R., Molenaar D., Kuipers O.P.,
RA   Leer R., Tarchini R., Peters S.A., Sandbrink H.M., Fiers M.W.E.J.,
RA   Stiekema W., Klein Lankhorst R.M., Bron P.A., Hoffer S.M.,
RA   Nierop Groot M.N., Kerkhoven R., De Vries M., Ursing B., De Vos W.M.,
RA   Siezen R.J.;
RT   "Complete genome sequence of Lactobacillus plantarum WCFS1.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:1990-1995(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-793 / NCIMB 8826 / WCFS1;
RX   PubMed=22156394; DOI=10.1128/jb.06275-11;
RA   Siezen R.J., Francke C., Renckens B., Boekhorst J., Wels M.,
RA   Kleerebezem M., van Hijum S.A.;
RT   "Complete resequencing and reannotation of the Lactobacillus plantarum
RT   WCFS1 genome.";
RL   J. Bacteriol. 194:195-196(2012).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the GRP transporter (TC 2.A.7.5) family.
CC       {ECO:0000305}.
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DR   EMBL; AL935263; CCC79741.1; -; Genomic_DNA.
DR   RefSeq; WP_011101841.1; NC_004567.2.
DR   RefSeq; YP_004890255.1; NC_004567.2.
DR   AlphaFoldDB; Q88UB3; -.
DR   SMR; Q88UB3; -.
DR   STRING; 220668.lp_2594; -.
DR   EnsemblBacteria; CCC79741; CCC79741; lp_2594.
DR   KEGG; lpl:lp_2594; -.
DR   PATRIC; fig|220668.9.peg.2177; -.
DR   eggNOG; COG4975; Bacteria.
DR   HOGENOM; CLU_076024_0_0_9; -.
DR   OMA; FCISMIS; -.
DR   PhylomeDB; Q88UB3; -.
DR   BioCyc; LPLA220668:G1GW0-2232-MON; -.
DR   Proteomes; UP000000432; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015144; F:carbohydrate transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR010651; Sugar_transport.
DR   PANTHER; PTHR16119; PTHR16119; 2.
DR   Pfam; PF06800; Sugar_transport; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Sugar transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..282
FT                   /note="Putative sugar uptake protein lp_2594"
FT                   /id="PRO_0000213654"
FT   TRANSMEM        2..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        31..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        53..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        90..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        119..136
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        146..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        176..194
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        209..226
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        233..252
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        262..281
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   282 AA;  30283 MW;  E4A1D5120D51B3CA CRC64;
     MIFLIAIIPA LCWGINPLLV GKINGHSENE MFGMGIGDGL IALIFWLFSQ PTVTISGVTF
     GLAMISGAAW AIGQLGQYIS YRLLGVSKTM PISTALQLVG TSLIGVLMFG EWGSSNQKIL
     GLLAIMLIVA GSALSAGTSD GRKKGFSCYL PLLMTTIGYW IYSCIPKLVK VDALQLFLPQ
     MLGILIVAVG WAIYHQPTVY RDKQSWQNTL PGILYGIAAF MYILSARSIG VTNAYIIGQL
     SVVISTLSGL FFLHERTGQQ SIVSVATGLL FIFMGCVTTA LI