ID   Y2597_MYCTU             Reviewed;         206 AA.
AC   P9WL73; L0TCV4; P65029; Q50624;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 27.
DE   RecName: Full=Uncharacterized protein Rv2597;
GN   OrderedLocusNames=Rv2597; ORFNames=MTCY227.04c;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL123456; CCP45393.1; -; Genomic_DNA.
DR   PIR; D70727; D70727.
DR   RefSeq; NP_217113.1; NC_000962.3.
DR   RefSeq; WP_003413441.1; NZ_NVQJ01000023.1.
DR   AlphaFoldDB; P9WL73; -.
DR   STRING; 83332.Rv2597; -.
DR   PaxDb; P9WL73; -.
DR   DNASU; 887679; -.
DR   GeneID; 45426599; -.
DR   GeneID; 887679; -.
DR   KEGG; mtu:Rv2597; -.
DR   TubercuList; Rv2597; -.
DR   eggNOG; ENOG502ZQSW; Bacteria.
DR   OMA; WAPDMPW; -.
DR   PhylomeDB; P9WL73; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; HDA:MTBBASE.
DR   InterPro; IPR025235; DUF4178.
DR   Pfam; PF13785; DUF4178; 1.
PE   1: Evidence at protein level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..206
FT                   /note="Uncharacterized protein Rv2597"
FT                   /id="PRO_0000104065"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   206 AA;  21943 MW;  E680A747F003225A CRC64;
     MGNLLVVIAV ALFIAAIVVL VVAIRRPKTP ATPGGRRDPL AFDAMPQFGP RQLGPGAIVS
     HGGIDYVVRG SVTFREGPFV WWEHLLEGGD TPTWLSVQED DGRLELAMWV KRTDLGLQPG
     GQHVIDGVTF QETERGHAGY TTEGTTGLPA GGEMDYVDCA SAGQGADESM LLSFERWAPD
     MGWEIATGKS VLAGELTVYP APPVSA