ID   Y2600_MYCTU             Reviewed;         152 AA.
AC   P9WFG5; L0TAC7; P68915; Q50621;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 28.
DE   RecName: Full=UPF0719 transmembrane protein Rv2600;
GN   OrderedLocusNames=Rv2600; ORFNames=MTCY227.01c;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0719 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CCP45396.1; Type=Erroneous termination; Note=Truncated C-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AL123456; CCP45396.1; ALT_SEQ; Genomic_DNA.
DR   PIR; G70727; G70727.
DR   RefSeq; NP_217116.1; NC_000962.3.
DR   AlphaFoldDB; P9WFG5; -.
DR   STRING; 83332.Rv2600; -.
DR   PaxDb; P9WFG5; -.
DR   DNASU; 887869; -.
DR   GeneID; 887869; -.
DR   KEGG; mtu:Rv2600; -.
DR   TubercuList; Rv2600; -.
DR   eggNOG; COG3766; Bacteria.
DR   OMA; WVERNRN; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007140; DUF350.
DR   Pfam; PF03994; DUF350; 2.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..152
FT                   /note="UPF0719 transmembrane protein Rv2600"
FT                   /id="PRO_0000104070"
FT   TRANSMEM        21..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        62..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        92..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        131..151
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   152 AA;  15648 MW;  D2CBC7B3DDA1E05A CRC64;
     MYQAGVDFGT ISLTPILHGV VATVLYFLVG AAVLVAGFLM VNLLTPGDLR RLVFIDRRPN
     AVVLAATMYV ALAIVTIAAI YASSNQLAQG LIGVAVYGIV GVALQGVALV ILEIAVPGRF
     REHIDAPALH PAVFATAVML LAVAGVIAAA LS