ID   Y260_STRP3              Reviewed;         229 AA.
AC   P0DA10; Q79WC6; Q8K8I9;
DT   27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT   27-JUL-2011, sequence version 1.
DT   25-MAY-2022, entry version 42.
DE   RecName: Full=Uncharacterized membrane protein SpyM3_0260;
GN   OrderedLocusNames=SpyM3_0260;
OS   Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=198466;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-595 / MGAS315;
RX   PubMed=12122206; DOI=10.1073/pnas.152298499;
RA   Beres S.B., Sylva G.L., Barbian K.D., Lei B., Hoff J.S., Mammarella N.D.,
RA   Liu M.-Y., Smoot J.C., Porcella S.F., Parkins L.D., Campbell D.S.,
RA   Smith T.M., McCormick J.K., Leung D.Y.M., Schlievert P.M., Musser J.M.;
RT   "Genome sequence of a serotype M3 strain of group A Streptococcus: phage-
RT   encoded toxins, the high-virulence phenotype, and clone emergence.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:10078-10083(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the BI1 family. {ECO:0000305}.
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DR   EMBL; AE014074; AAM78867.1; -; Genomic_DNA.
DR   RefSeq; WP_011054209.1; NC_004070.1.
DR   AlphaFoldDB; P0DA10; -.
DR   SMR; P0DA10; -.
DR   EnsemblBacteria; AAM78867; AAM78867; SpyM3_0260.
DR   KEGG; spg:SpyM3_0260; -.
DR   HOGENOM; CLU_058671_1_2_9; -.
DR   OMA; SHNAYAE; -.
DR   Proteomes; UP000000564; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006214; Bax_inhibitor_1-related.
DR   PANTHER; PTHR23291; PTHR23291; 1.
DR   Pfam; PF01027; Bax1-I; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..229
FT                   /note="Uncharacterized membrane protein SpyM3_0260"
FT                   /id="PRO_0000179114"
FT   TRANSMEM        21..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        56..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        83..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        109..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        141..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        162..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        202..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   229 AA;  24944 MW;  2BB5AA4995571063 CRC64;
     MNDHVIYTQS DVGLNQFFAK IYSLVGMGVG LSAFVSYLML YPFRENLISI LVNQPMIYYG
     AAIIELILVF VASGAARKNT PAALPIFLIY AALNGFTLSF IIVAYAQTTV FQAFLSSAAV
     FFAMSIIGVK TKRDMSGLRK AMFAALIGVV VASLINLFIG SGMMSYVISV ISVLIFSGLI
     ASDNQMIKRV YQATNGQVGD GWAVAMALSL YLDFINLFIS LLRIFGRND