ID   Y260_STRPQ              Reviewed;         229 AA.
AC   P0DA11; Q79WC6; Q8K8I9;
DT   27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT   27-JUL-2011, sequence version 1.
DT   25-MAY-2022, entry version 40.
DE   RecName: Full=Uncharacterized membrane protein SPs1599;
GN   OrderedLocusNames=SPs1599;
OS   Streptococcus pyogenes serotype M3 (strain SSI-1).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=193567;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SSI-1;
RX   PubMed=12799345; DOI=10.1101/gr.1096703;
RA   Nakagawa I., Kurokawa K., Yamashita A., Nakata M., Tomiyasu Y.,
RA   Okahashi N., Kawabata S., Yamazaki K., Shiba T., Yasunaga T., Hayashi H.,
RA   Hattori M., Hamada S.;
RT   "Genome sequence of an M3 strain of Streptococcus pyogenes reveals a large-
RT   scale genomic rearrangement in invasive strains and new insights into phage
RT   evolution.";
RL   Genome Res. 13:1042-1055(2003).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the BI1 family. {ECO:0000305}.
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DR   EMBL; BA000034; BAC64694.1; -; Genomic_DNA.
DR   RefSeq; WP_011054209.1; NC_004606.1.
DR   AlphaFoldDB; P0DA11; -.
DR   SMR; P0DA11; -.
DR   KEGG; sps:SPs1599; -.
DR   HOGENOM; CLU_058671_1_2_9; -.
DR   OMA; SHNAYAE; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006214; Bax_inhibitor_1-related.
DR   PANTHER; PTHR23291; PTHR23291; 1.
DR   Pfam; PF01027; Bax1-I; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..229
FT                   /note="Uncharacterized membrane protein SPs1599"
FT                   /id="PRO_0000411293"
FT   TRANSMEM        21..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        56..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        83..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        109..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        141..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        162..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        202..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   229 AA;  24944 MW;  2BB5AA4995571063 CRC64;
     MNDHVIYTQS DVGLNQFFAK IYSLVGMGVG LSAFVSYLML YPFRENLISI LVNQPMIYYG
     AAIIELILVF VASGAARKNT PAALPIFLIY AALNGFTLSF IIVAYAQTTV FQAFLSSAAV
     FFAMSIIGVK TKRDMSGLRK AMFAALIGVV VASLINLFIG SGMMSYVISV ISVLIFSGLI
     ASDNQMIKRV YQATNGQVGD GWAVAMALSL YLDFINLFIS LLRIFGRND