ID   Y260_SYNY3              Reviewed;         448 AA.
AC   P74409;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   25-MAY-2022, entry version 134.
DE   RecName: Full=UPF0053 protein sll0260;
GN   OrderedLocusNames=sll0260;
OS   Synechocystis sp. (strain PCC 6803 / Kazusa).
OC   Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae; Synechocystis;
OC   unclassified Synechocystis.
OX   NCBI_TaxID=1111708;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6803 / Kazusa;
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0053 family. {ECO:0000305}.
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DR   EMBL; BA000022; BAA18507.1; -; Genomic_DNA.
DR   PIR; S76248; S76248.
DR   AlphaFoldDB; P74409; -.
DR   SMR; P74409; -.
DR   STRING; 1148.1653594; -.
DR   PaxDb; P74409; -.
DR   EnsemblBacteria; BAA18507; BAA18507; BAA18507.
DR   KEGG; syn:sll0260; -.
DR   eggNOG; COG1253; Bacteria.
DR   InParanoid; P74409; -.
DR   OMA; YLTMEDV; -.
DR   PhylomeDB; P74409; -.
DR   Proteomes; UP000001425; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR   Gene3D; 3.10.580.10; -; 1.
DR   Gene3D; 3.30.465.10; -; 1.
DR   InterPro; IPR000644; CBS_dom.
DR   InterPro; IPR046342; CBS_dom_sf.
DR   InterPro; IPR002550; CNNM.
DR   InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR   InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR   InterPro; IPR044751; Ion_transp-like_CBS.
DR   InterPro; IPR005170; Transptr-assoc_dom.
DR   Pfam; PF00571; CBS; 1.
DR   Pfam; PF03471; CorC_HlyC; 1.
DR   Pfam; PF01595; DUF21; 1.
DR   SMART; SM01091; CorC_HlyC; 1.
DR   SUPFAM; SSF54631; SSF54631; 1.
DR   SUPFAM; SSF56176; SSF56176; 1.
DR   PROSITE; PS51371; CBS; 2.
DR   PROSITE; PS51846; CNNM; 1.
PE   3: Inferred from homology;
KW   CBS domain; Cell membrane; Membrane; Reference proteome; Repeat;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..448
FT                   /note="UPF0053 protein sll0260"
FT                   /id="PRO_0000088383"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        62..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        106..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        142..162
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          2..203
FT                   /note="CNNM transmembrane"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01193"
FT   DOMAIN          222..281
FT                   /note="CBS 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT   DOMAIN          286..345
FT                   /note="CBS 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
SQ   SEQUENCE   448 AA;  49227 MW;  1DC3D3860A4765FA CRC64;
     MFSSSVELEL FFIFVLVVLN GIFSGSEIAI VSARKVRLEQ LAKRGNRKAK LALKLATAPN
     NFLSAVQIGI TLIGILTGAV GGATVALRLA EFLDDIPLLA PYAGPLSISL LVGFITYLSL
     VVGELVPKRI ALSHPEHIAC GVAPAMHLVA QLTAPLVYLL GVSTDAVLRL FGITSKEASP
     ITEEEIRVMI EQGAQAGMID EAEQEMVERV FRLGDRPVKT LMTPRTAIAW LDVESDWEEN
     QQEILDTPYS RFPVGRDSLD ECLGFVRVKD ILNSQWSGQK INLEEIVQPP LFVAENTRSL
     HVLEMFRASG THLALITDEY GGIEGLVTLN DLIEAIVGSI PNDDEIQEPQ IIQREDGSYL
     LDGLLPIDEF KEIFDIETLS NEEEGHYHTL GGFVIESLGK IPQSGDYFVS DTLRVEVVDM
     DGIRIDKVLV NQLPEDSSTT EEESETDN