ID   Y260_TREPA              Reviewed;         448 AA.
AC   O83284;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 98.
DE   RecName: Full=Uncharacterized protein TP_0260;
GN   OrderedLocusNames=TP_0260;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AE000520; AAC65253.1; -; Genomic_DNA.
DR   PIR; A71347; A71347.
DR   RefSeq; WP_010881709.1; NC_021490.2.
DR   AlphaFoldDB; O83284; -.
DR   IntAct; O83284; 11.
DR   STRING; 243276.TPANIC_0260; -.
DR   EnsemblBacteria; AAC65253; AAC65253; TP_0260.
DR   KEGG; tpa:TP_0260; -.
DR   eggNOG; ENOG5033XG8; Bacteria.
DR   HOGENOM; CLU_628383_0_0_12; -.
DR   OMA; NIKYLRP; -.
DR   OrthoDB; 440349at2; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR003646; SH3-like_bac-type.
DR   Pfam; PF08239; SH3_3; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR   PROSITE; PS51781; SH3B; 1.
PE   4: Predicted;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..448
FT                   /note="Uncharacterized protein TP_0260"
FT                   /id="PRO_0000202220"
FT   TRANSMEM        19..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          105..181
FT                   /note="SH3b"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01117"
SQ   SEQUENCE   448 AA;  51247 MW;  F5DCAE035E30B5EB CRC64;
     MCYYRYVQVH SIWRRFCALG LLVPFLLLLF SCTNTVGYGV LQWSLPDLGL STGDILPVYV
     RSNVSQVYIV EIQKKKVELP FWQLKLCRTK KEALQYAERL REYRYSYATS VLDGLPLREG
     PENTAPQVYR LREGQAVKLL WKGTGKAVYR GENRLEGDWF KVMTEDGTTG WCFSHGLSLF
     DERESRPTVR ETDDLARDRD LQHVLNSAWY PEYYRTMVEQ RRIDLEKMAS GWGLFVGEKK
     GLARIELPDA HYAFPYSRLV KTGSNGYLFD GSSLSIYVRD AHTLAAQFTD EAGRLRIERF
     VTLEKTPEEI IAEEQLRRSA LLEHVCTPGL RLHSEIYGTL SFTERNVFTW TGARALSPAL
     IPAGAGSTGR VALRCFIDQS LKSEYEGVLS FDFDSAQEWV HFLYLRTPGG LKLEHIDSTH
     LKDATVLRRS VSPVVLYFAP EGHAEPQP