ID   Y2631_MYCTA             Reviewed;         251 AA.
AC   A5U5V4;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Probable transcriptional regulatory protein MRA_2631 {ECO:0000255|HAMAP-Rule:MF_00693};
GN   OrderedLocusNames=MRA_2631;
OS   Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=419947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25177 / H37Ra;
RX   PubMed=18584054; DOI=10.1371/journal.pone.0002375;
RA   Zheng H., Lu L., Wang B., Pu S., Zhang X., Zhu G., Shi W., Zhang L.,
RA   Wang H., Wang S., Zhao G., Zhang Y.;
RT   "Genetic basis of virulence attenuation revealed by comparative genomic
RT   analysis of Mycobacterium tuberculosis strain H37Ra versus H37Rv.";
RL   PLoS ONE 3:E2375-E2375(2008).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00693}.
CC   -!- SIMILARITY: Belongs to the TACO1 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00693}.
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DR   EMBL; CP000611; ABQ74404.1; -; Genomic_DNA.
DR   RefSeq; WP_003413464.1; NZ_CP016972.1.
DR   AlphaFoldDB; A5U5V4; -.
DR   SMR; A5U5V4; -.
DR   STRING; 419947.MRA_2631; -.
DR   EnsemblBacteria; ABQ74404; ABQ74404; MRA_2631.
DR   GeneID; 45426606; -.
DR   KEGG; mra:MRA_2631; -.
DR   eggNOG; COG0217; Bacteria.
DR   HOGENOM; CLU_062974_2_2_11; -.
DR   OMA; ETIMYEG; -.
DR   OrthoDB; 1304328at2; -.
DR   Proteomes; UP000001988; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.200; -; 1.
DR   Gene3D; 3.30.70.980; -; 2.
DR   HAMAP; MF_00693; Transcrip_reg_TACO1; 1.
DR   InterPro; IPR017856; Integrase-like_N.
DR   InterPro; IPR002876; Transcrip_reg_TACO1-like.
DR   InterPro; IPR026564; Transcrip_reg_TACO1-like_dom3.
DR   InterPro; IPR029072; YebC-like.
DR   PANTHER; PTHR12532; PTHR12532; 1.
DR   Pfam; PF01709; Transcrip_reg; 1.
DR   SUPFAM; SSF75625; SSF75625; 1.
DR   TIGRFAMs; TIGR01033; TIGR01033; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..251
FT                   /note="Probable transcriptional regulatory protein
FT                   MRA_2631"
FT                   /id="PRO_1000045342"
SQ   SEQUENCE   251 AA;  26799 MW;  B163D43729A06B33 CRC64;
     MSGHSKWATT KHKKAVVDAR RGKMFARLIK NIEVAARVGG GDPAGNPTLY DAIQKAKKSS
     VPNENIERAR KRGAGEEAGG ADWQTIMYEG YAPNGVAVLI ECLTDNRNRA ASEVRVAMTR
     NGGTMADPGS VSYLFSRKGV VTLEKNGLTE DDVLAAVLEA GAEDVNDLGD SFEVISEPAE
     LVAVRSALQD AGIDYESAEA SFQPSVSVPV DLDGARKVFK LVDALEDSDD VQNVWTNVDV
     SDEVLAALDD E