ID   Y2639_MYCTU             Reviewed;         110 AA.
AC   P9WFN9; L0TD48; P67146; P71938;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 30.
DE   RecName: Full=UPF0060 membrane protein Rv2639c {ECO:0000255|HAMAP-Rule:MF_00010};
GN   OrderedLocusNames=Rv2639c; ORFNames=MTCY441.09c;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00010};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00010}.
CC   -!- SIMILARITY: Belongs to the UPF0060 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00010}.
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DR   EMBL; AL123456; CCP45437.1; -; Genomic_DNA.
DR   PIR; C70964; C70964.
DR   RefSeq; NP_217155.1; NC_000962.3.
DR   RefSeq; WP_003413663.1; NZ_NVQJ01000077.1.
DR   AlphaFoldDB; P9WFN9; -.
DR   STRING; 83332.Rv2639c; -.
DR   PaxDb; P9WFN9; -.
DR   DNASU; 887428; -.
DR   GeneID; 45426644; -.
DR   GeneID; 887428; -.
DR   KEGG; mtu:Rv2639c; -.
DR   TubercuList; Rv2639c; -.
DR   eggNOG; COG1742; Bacteria.
DR   OMA; GWLWAVD; -.
DR   PhylomeDB; P9WFN9; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0005576; C:extracellular region; HDA:MTBBASE.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   HAMAP; MF_00010; UPF0060; 1.
DR   InterPro; IPR003844; UPF0060.
DR   PANTHER; PTHR36116; PTHR36116; 1.
DR   Pfam; PF02694; UPF0060; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..110
FT                   /note="UPF0060 membrane protein Rv2639c"
FT                   /id="PRO_0000162333"
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00010"
FT   TRANSMEM        32..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00010"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00010"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00010"
SQ   SEQUENCE   110 AA;  11720 MW;  9F13862B9195EFBB CRC64;
     MVVRSILLFV LAAVAEIGGA WLVWQGVREQ RGWLWAGLGV IALGVYGFFA TLQPDAHFGR
     VLAAYGGVFV AGSLAWGMAL DGFRPDRWDV IGALGCMAGV AVIMYAPRGH