ID   Y2644_ALKHC             Reviewed;         354 AA.
AC   Q9K9K2;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=UPF0421 protein BH2644;
GN   OrderedLocusNames=BH2644;
OS   Alkalihalobacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344
OS   / JCM 9153 / C-125) (Bacillus halodurans).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Alkalihalobacillus.
OX   NCBI_TaxID=272558;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125;
RX   PubMed=11058132; DOI=10.1093/nar/28.21.4317;
RA   Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F.,
RA   Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.;
RT   "Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans
RT   and genomic sequence comparison with Bacillus subtilis.";
RL   Nucleic Acids Res. 28:4317-4331(2000).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0421 family. {ECO:0000305}.
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DR   EMBL; BA000004; BAB06363.1; -; Genomic_DNA.
DR   PIR; D83980; D83980.
DR   RefSeq; WP_010898794.1; NC_002570.2.
DR   AlphaFoldDB; Q9K9K2; -.
DR   SMR; Q9K9K2; -.
DR   STRING; 272558.10175265; -.
DR   EnsemblBacteria; BAB06363; BAB06363; BAB06363.
DR   KEGG; bha:BH2644; -.
DR   eggNOG; COG4129; Bacteria.
DR   HOGENOM; CLU_067028_0_0_9; -.
DR   OMA; ANVMEEW; -.
DR   OrthoDB; 1974930at2; -.
DR   Proteomes; UP000001258; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR010343; ArAE_1.
DR   Pfam; PF06081; ArAE_1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..354
FT                   /note="UPF0421 protein BH2644"
FT                   /id="PRO_0000283010"
FT   TRANSMEM        22..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        60..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        107..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        133..153
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   354 AA;  40019 MW;  C81A7B39DCF3F2DA CRC64;
     MEISGFMKHP WIGRRVLKTG LAVCLTTAIC MAFNLSPTFA VISAIVTTEP TAADSLKKGL
     IRLPAAALGA FFAVLSAYFF GQTPITYAIV SMITIAVCAR LRLDAGTLVA TLTAVAMIPS
     TTDHLFADYV SRVAGTSLGI MISTFVNFMI LPPKFGPILM NKVEKMFAML SSELKLVTTK
     VVDFEKEETM TSYRTLHHHL SETYKLTTFQ HDEWKYRKSS SSEKRSFTYL HRKLDYVYKA
     LAHLGKIGQI RLKKPLSVKE RQLVLSFLVS LTNILQDPLH QIHTEHYALA RQLEDAMHKK
     KDATEPIHRL LSELISLHDL TVELEQCTAD ERRFSLEERA YPSYIFLERL RPSD