Y2653_MYCTO
ID Y2653_MYCTO Reviewed; 107 AA.
AC P9WJ12; L0TAH9; P71950; Q7D6U1;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 32.
DE RecName: Full=Toxin MT2730;
GN OrderedLocusNames=MT2730;
OS Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83331;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 1551 / Oshkosh;
RX PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT laboratory strains.";
RL J. Bacteriol. 184:5479-5490(2002).
CC -!- FUNCTION: Toxic component of a type II toxin-antitoxin (TA) system. Its
CC toxic effect is neutralized by coexpression with cognate antitoxin
CC MT2731 (By similarity). {ECO:0000250}.
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DR EMBL; AE000516; AAK47044.1; -; Genomic_DNA.
DR PIR; A70966; A70966.
DR RefSeq; WP_003899414.1; NZ_KK341227.1.
DR AlphaFoldDB; P9WJ12; -.
DR SMR; P9WJ12; -.
DR EnsemblBacteria; AAK47044; AAK47044; MT2730.
DR KEGG; mtc:MT2730; -.
DR PATRIC; fig|83331.31.peg.2940; -.
DR HOGENOM; CLU_153838_0_0_11; -.
DR Proteomes; UP000001020; Chromosome.
PE 3: Inferred from homology;
KW Toxin-antitoxin system.
FT CHAIN 1..107
FT /note="Toxin MT2730"
FT /id="PRO_0000427910"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 107 AA; 12360 MW; 8E491FB29CB65D56 CRC64;
MTHKRTKRQP AIAAGLNAPR RNRVGRQHGW PADVPSAEQR RAQRQRDLEA IRRAYAEMVA
TSHEIDDDTA ELALLSMHLD DEQRRLEAGM KLGWHPYHFP DEPDSKQ