ID   Y2657_BORBR             Reviewed;         565 AA.
AC   Q7WJ43;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Uncharacterized transporter BB2657;
GN   OrderedLocusNames=BB2657;
OS   Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)
OS   (Alcaligenes bronchisepticus).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Alcaligenaceae; Bordetella.
OX   NCBI_TaxID=257310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-588 / NCTC 13252 / RB50;
RX   PubMed=12910271; DOI=10.1038/ng1227;
RA   Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R.,
RA   Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L.,
RA   Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A.,
RA   Achtman M., Atkin R., Baker S., Basham D., Bason N., Cherevach I.,
RA   Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T.,
RA   Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S.,
RA   Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E.,
RA   Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M.,
RA   Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S.,
RA   Barrell B.G., Maskell D.J.;
RT   "Comparative analysis of the genome sequences of Bordetella pertussis,
RT   Bordetella parapertussis and Bordetella bronchiseptica.";
RL   Nat. Genet. 35:32-40(2003).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the AAE transporter (TC 2.A.81) family.
CC       {ECO:0000305}.
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DR   EMBL; BX640445; CAE33150.1; -; Genomic_DNA.
DR   RefSeq; WP_003811697.1; NC_002927.3.
DR   AlphaFoldDB; Q7WJ43; -.
DR   SMR; Q7WJ43; -.
DR   EnsemblBacteria; CAE33150; CAE33150; BB2657.
DR   GeneID; 56478769; -.
DR   KEGG; bbr:BB2657; -.
DR   eggNOG; COG2985; Bacteria.
DR   HOGENOM; CLU_035023_2_2_4; -.
DR   OMA; VYPLGMF; -.
DR   OrthoDB; 1458740at2; -.
DR   Proteomes; UP000001027; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR   Gene3D; 3.30.70.1450; -; 1.
DR   InterPro; IPR006037; RCK_C.
DR   InterPro; IPR036721; RCK_C_sf.
DR   InterPro; IPR006512; YidE_YbjL.
DR   Pfam; PF06826; Asp-Al_Ex; 2.
DR   Pfam; PF02080; TrkA_C; 1.
DR   SUPFAM; SSF116726; SSF116726; 1.
DR   TIGRFAMs; TIGR01625; YidE_YbjL_dupl; 1.
DR   PROSITE; PS51202; RCK_C; 2.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Repeat; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..565
FT                   /note="Uncharacterized transporter BB2657"
FT                   /id="PRO_0000208759"
FT   TRANSMEM        4..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        33..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        68..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        97..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        162..184
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        389..411
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        415..432
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        453..472
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        482..504
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        539..561
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          210..295
FT                   /note="RCK C-terminal 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00544"
FT   DOMAIN          296..379
FT                   /note="RCK C-terminal 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00544"
SQ   SEQUENCE   565 AA;  59266 MW;  5F65533FF707E6F3 CRC64;
     MQAFVQFLGS NPYILLFLTI GLAVWVGKFS IKGYGLGAVA AAIVVGCLVA TVGAAYGVKF
     HLDEFAKSLL YYLFMYGVGL RVGPSFVNAL NKESINYAIL AIIAPILGLA IVVLGTQFFG
     LPLGAAGGML AGSQTMSAAI GSAEQAVSAG VLSLGSESPE QISAMIALSY GITYIWGTVG
     IILLCKYLPR IWGVDAKAAA LEFEKAHGVP NVDDAGLTAF HPFDLRAYRV ENPESIGKTV
     QQFRTRFPQY QVVNVERGDQ LLGPSAETVL QQGDVVALGG RLEEMTANMG VLGPEVPDAR
     ALNIPLDQAE ILVTNKEVTG RPLKTFRGSE LAGQIQLQRV ERSGVPLPIG LETTLQKRDV
     LFVTGLQPAV SKAGEIFGVI ARHSSATDLL TLSFGMILGF LIGLIEVPAF GAKVGLGNAG
     GLLLSGIIVS SISSRLRFFG NTPNAARNIL EDLGLIGFVA IVGINAGADL LTQLTGAIAL
     KIFIVGFLAS TIPPIIVWAI GFHIMKINPA LLMGATAGAR SHSGPAREAA KEVGSSVPWL
     GFPVGYAVSG VLLTVFGYFA MVLAH