ID   Y2662_VIBCM             Reviewed;         297 AA.
AC   C3LSG9;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-JUN-2009, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=UPF0761 membrane protein VCM66_2662 {ECO:0000255|HAMAP-Rule:MF_00672};
GN   OrderedLocusNames=VCM66_2662;
OS   Vibrio cholerae serotype O1 (strain M66-2).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=579112;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M66-2;
RX   PubMed=19115014; DOI=10.1371/journal.pone.0004053;
RA   Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J.,
RA   Wang W., Wang J., Qian W., Li D., Wang L.;
RT   "A recalibrated molecular clock and independent origins for the cholera
RT   pandemic clones.";
RL   PLoS ONE 3:E4053-E4053(2008).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_00672}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_00672}.
CC   -!- SIMILARITY: Belongs to the UPF0761 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00672}.
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DR   EMBL; CP001233; ACP06956.1; -; Genomic_DNA.
DR   RefSeq; WP_001884068.1; NC_012578.1.
DR   AlphaFoldDB; C3LSG9; -.
DR   EnsemblBacteria; ACP06956; ACP06956; VCM66_2662.
DR   GeneID; 57741333; -.
DR   KEGG; vcm:VCM66_2662; -.
DR   HOGENOM; CLU_032288_0_0_6; -.
DR   OMA; KQPKFRW; -.
DR   Proteomes; UP000001217; Chromosome I.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00672; UPF0761; 1.
DR   InterPro; IPR023679; UPF0761_bac.
DR   InterPro; IPR017039; Virul_fac_BrkB.
DR   PANTHER; PTHR30213; PTHR30213; 1.
DR   Pfam; PF03631; Virul_fac_BrkB; 1.
DR   PIRSF; PIRSF035875; RNase_BN; 1.
DR   TIGRFAMs; TIGR00765; yihY_not_rbn; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..297
FT                   /note="UPF0761 membrane protein VCM66_2662"
FT                   /id="PRO_1000147671"
FT   TRANSMEM        43..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
FT   TRANSMEM        100..120
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
FT   TRANSMEM        135..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
FT   TRANSMEM        181..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
FT   TRANSMEM        213..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
FT   TRANSMEM        245..265
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
SQ   SEQUENCE   297 AA;  33286 MW;  10BCF576215B8481 CRC64;
     MKLTHSFIKQ QARLGLNFFR YLLARMNHDR VNVNAGYLAY ITLLSMVPML TVLLSILSSF
     ALFANAGEVI QDFVITHFVP AAGEVVKTAL IEFVANTGKM TAVGGAFLFV AAIMLISNID
     KNLNYIWRVQ QKRRAVFSFS MYWMILTLGP ILVGASIAAT SYITSLKILD NEALSGVYNL
     FLRWLPFVLS YCAFVGLYLL VPNKKVHWQH AMLGALIAAI LFELSKKGFA AYITQFPSYQ
     LIYGALAAIP ILFVWVYLCW LIVLVGAEVT AALGEREHWS DSQDMLHFAP LPKNEKE