ID   Y266_LISIN              Reviewed;         357 AA.
AC   Q92F41;
DT   23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Uncharacterized PIN and TRAM-domain containing protein Lin0266;
DE   AltName: Full=Putative RNase Lin0266;
DE            EC=3.1.-.-;
GN   OrderedLocusNames=lin0266;
OS   Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Listeriaceae; Listeria.
OX   NCBI_TaxID=272626;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-680 / CLIP 11262;
RX   PubMed=11679669; DOI=10.1126/science.1063447;
RA   Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A., Baquero F.,
RA   Berche P., Bloecker H., Brandt P., Chakraborty T., Charbit A.,
RA   Chetouani F., Couve E., de Daruvar A., Dehoux P., Domann E.,
RA   Dominguez-Bernal G., Duchaud E., Durant L., Dussurget O., Entian K.-D.,
RA   Fsihi H., Garcia-del Portillo F., Garrido P., Gautier L., Goebel W.,
RA   Gomez-Lopez N., Hain T., Hauf J., Jackson D., Jones L.-M., Kaerst U.,
RA   Kreft J., Kuhn M., Kunst F., Kurapkat G., Madueno E., Maitournam A.,
RA   Mata Vicente J., Ng E., Nedjari H., Nordsiek G., Novella S., de Pablos B.,
RA   Perez-Diaz J.-C., Purcell R., Remmel B., Rose M., Schlueter T., Simoes N.,
RA   Tierrez A., Vazquez-Boland J.-A., Voss H., Wehland J., Cossart P.;
RT   "Comparative genomics of Listeria species.";
RL   Science 294:849-852(2001).
CC   -!- FUNCTION: An RNase. {ECO:0000305}.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000305};
CC   -!- SIMILARITY: Belongs to the ycf81 family. {ECO:0000305}.
CC   -!- SIMILARITY: In the central section; belongs to the PINc/VapC protein
CC       family. {ECO:0000305}.
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DR   EMBL; AL596164; CAC95499.1; -; Genomic_DNA.
DR   PIR; AC1466; AC1466.
DR   RefSeq; WP_003770118.1; NC_003212.1.
DR   AlphaFoldDB; Q92F41; -.
DR   SMR; Q92F41; -.
DR   STRING; 272626.lin0266; -.
DR   EnsemblBacteria; CAC95499; CAC95499; CAC95499.
DR   GeneID; 61169260; -.
DR   KEGG; lin:lin0266; -.
DR   eggNOG; COG4956; Bacteria.
DR   HOGENOM; CLU_050839_0_0_9; -.
DR   OMA; TMPTDLL; -.
DR   OrthoDB; 940436at2; -.
DR   Proteomes; UP000002513; Chromosome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   InterPro; IPR002716; PIN_dom.
DR   InterPro; IPR002792; TRAM_dom.
DR   SMART; SM00670; PINc; 1.
DR   SUPFAM; SSF88723; SSF88723; 1.
DR   PROSITE; PS50926; TRAM; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Magnesium; Metal-binding; Nuclease.
FT   CHAIN           1..357
FT                   /note="Uncharacterized PIN and TRAM-domain containing
FT                   protein Lin0266"
FT                   /id="PRO_0000217412"
FT   DOMAIN          166..278
FT                   /note="PINc"
FT   DOMAIN          292..353
FT                   /note="TRAM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00208"
FT   BINDING         229
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000255"
FT   BINDING         247
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   357 AA;  39433 MW;  23A6C248979167F4 CRC64;
     MLTWVIRVCF LILGGTTGVF SLPALWVKLG IGHILLINNP YTDALIGALI FYLITFWAVK
     YVEAALNWLE EKLAKIAIAT LIYGGLGLFV GLVIAFFASN ALSQTNIPLL NSVVPVILTL
     VLGYLGFRIG ISRRNEFGNF VNNRNAKKKT PEEEQTEEKS KKTYKILDTS VIIDGRIADI
     LATGFLDGTV VIPLFVLAEL QHIADSSDTL KRTRGRRGLD ILNRIQKEDS IQVEMYEGDF
     EDTPEVDSKL VKLAKVMGGI VVTNDYNLNK VCEFQNVPVL NINDLANAVK PVVLPGEKMT
     VLMVKDGKEH NQGVAYLDDG TMIVVEDGRK FINETIQVEV TSVLQTSAGR MIFAKPS