ID   Y2684_MYCTO             Reviewed;         429 AA.
AC   P9WPD8; L0TD93; O07186; P0A606;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 27.
DE   RecName: Full=Uncharacterized transporter MT2758;
GN   OrderedLocusNames=MT2758;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CitM (TC 2.A.11) transporter family.
CC       {ECO:0000305}.
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DR   EMBL; AE000516; AAK47073.1; -; Genomic_DNA.
DR   PIR; G70528; G70528.
DR   RefSeq; WP_003917669.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WPD8; -.
DR   SMR; P9WPD8; -.
DR   EnsemblBacteria; AAK47073; AAK47073; MT2758.
DR   KEGG; mtc:MT2758; -.
DR   PATRIC; fig|83331.31.peg.2970; -.
DR   HOGENOM; CLU_011920_4_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015105; F:arsenite transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR000802; Arsenical_pump_ArsB.
DR   InterPro; IPR004680; Cit_transptr-like_dom.
DR   Pfam; PF03600; CitMHS; 1.
DR   PRINTS; PR00758; ARSENICPUMP.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..429
FT                   /note="Uncharacterized transporter MT2758"
FT                   /id="PRO_0000426969"
FT   TRANSMEM        26..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        51..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        99..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        135..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        173..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        223..243
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        278..298
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        311..331
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        361..381
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        407..427
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   429 AA;  45160 MW;  255A10C7766CABC8 CRC64;
     MSVVAVTIFV AAYVLIASDR VNKTMVALTG AAAVVVLPVI TSHDIFYSHD TGIDWDVIFL
     LVGMMIIVGV LRQTGVFEYT AIWAAKRARG SPLRIMILLV LVSALASALL DNVTTVLLIA
     PVTLLVCDRL NINTTSFLMA EVFASNIGGA ATLVGDPPNI IVASRAGLTF NDFMLHLTPL
     VVIVLIALIA VLPRLFGSIT VEADRIADVM ALDEGEAIRD RGLLVKCGAV LVLVFAAFVA
     HPVLHIQPSL VALLGAGMLI AVSGLTRSEY LSSVEWDTLL FFAGLFIMVG ALVKTGVVND
     LARAATQLTG GNIVATAFLI LGVSAPISGI IDNIPYVATM TPLVAELVAV MGGQPSTDTP
     WWALALGADF GGNLTAIGAS ANVVMLGIAR RAGAPISFWE FTRKGAVVTA VSIALAAIYL
     WLRYFVLLH