ID   Y2703_MYCBO             Reviewed;         429 AA.
AC   P0A607; A0A1R3Y1W3; O07186; X2BL67;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=Uncharacterized transporter Mb2703;
GN   OrderedLocusNames=BQ2027_MB2703;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CitM (TC 2.A.11) transporter family.
CC       {ECO:0000305}.
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DR   EMBL; LT708304; SIU01321.1; -; Genomic_DNA.
DR   RefSeq; NP_856349.1; NC_002945.3.
DR   RefSeq; WP_003413894.1; NC_002945.4.
DR   AlphaFoldDB; P0A607; -.
DR   SMR; P0A607; -.
DR   TCDB; 2.A.45.2.2; the arsenite-antimonite (arsb) efflux family.
DR   EnsemblBacteria; SIU01321; SIU01321; BQ2027_MB2703.
DR   PATRIC; fig|233413.5.peg.2963; -.
DR   OMA; IAMFIDV; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015105; F:arsenite transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR000802; Arsenical_pump_ArsB.
DR   InterPro; IPR004680; Cit_transptr-like_dom.
DR   Pfam; PF03600; CitMHS; 1.
DR   PRINTS; PR00758; ARSENICPUMP.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..429
FT                   /note="Uncharacterized transporter Mb2703"
FT                   /id="PRO_0000172513"
FT   TRANSMEM        26..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        51..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        99..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        135..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        173..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        223..243
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        278..298
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        311..331
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        361..381
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        407..427
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   429 AA;  45188 MW;  F9076F9CAC57B86A CRC64;
     MSVVAVTIFV AAYVLIASDR VNKTMVALTG AAAVVVLPVI TSHDIFYSHD TGIDWDVIFL
     LVGMMIIVGV LRQTGVFEYT AIWAAKRARG SPLRIMILLV LVSALASALL DNVTTVLLIA
     PVTLLVCDRL NINTTSFLMA EVFASNIGGA ATLVGDPPNI IVASRAGLTF NDFMLHLTPL
     VVIVLIALIA VLPRLFGSIT VEADRIADVM ALDEGEAIRD RGLLVKCGAV LVLVFAAFVA
     HPVLHIQPSL VALLGAGMLI VVSGLTRSEY LSSVEWDTLL FFAGLFIMVG ALVKTGVVND
     LARAATQLTG GNIVATAFLI LGVSAPISGI IDNIPYVATM TPLVAELVAV MGGQPSTDTP
     WWALALGADF GGNLTAIGAS ANVVMLGIAR RAGAPISFWE FTRKGAVVTA VSIALAAIYL
     WLRYFVLLH