ID   Y2714_LISMO             Reviewed;         315 AA.
AC   Q8Y3W5;
DT   05-DEC-2018, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Cell wall protein Lmo2714 {ECO:0000305};
DE   AltName: Full=Wall-associated protein lmo2714 {ECO:0000305};
DE   Flags: Precursor;
GN   OrderedLocusNames=lmo2714;
OS   Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Listeriaceae; Listeria.
OX   NCBI_TaxID=169963;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-679 / EGD-e;
RX   PubMed=11679669; DOI=10.1126/science.1063447;
RA   Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A., Baquero F.,
RA   Berche P., Bloecker H., Brandt P., Chakraborty T., Charbit A.,
RA   Chetouani F., Couve E., de Daruvar A., Dehoux P., Domann E.,
RA   Dominguez-Bernal G., Duchaud E., Durant L., Dussurget O., Entian K.-D.,
RA   Fsihi H., Garcia-del Portillo F., Garrido P., Gautier L., Goebel W.,
RA   Gomez-Lopez N., Hain T., Hauf J., Jackson D., Jones L.-M., Kaerst U.,
RA   Kreft J., Kuhn M., Kunst F., Kurapkat G., Madueno E., Maitournam A.,
RA   Mata Vicente J., Ng E., Nedjari H., Nordsiek G., Novella S., de Pablos B.,
RA   Perez-Diaz J.-C., Purcell R., Remmel B., Rose M., Schlueter T., Simoes N.,
RA   Tierrez A., Vazquez-Boland J.-A., Voss H., Wehland J., Cossart P.;
RT   "Comparative genomics of Listeria species.";
RL   Science 294:849-852(2001).
RN   [2]
RP   PROTEIN SEQUENCE OF 123-143, PROCESSING BY SRTA, AND SUBCELLULAR LOCATION.
RC   STRAIN=ATCC BAA-679 / EGD-e;
RX   PubMed=11929538; DOI=10.1046/j.1365-2958.2002.02798.x;
RA   Bierne H., Mazmanian S.K., Trost M., Pucciarelli M.G., Liu G., Dehoux P.,
RA   Jansch L., Garcia-del Portillo F., Schneewind O., Cossart P.;
RT   "Inactivation of the srtA gene in Listeria monocytogenes inhibits anchoring
RT   of surface proteins and affects virulence.";
RL   Mol. Microbiol. 43:869-881(2002).
RN   [3]
RP   IDENTIFICATION BY MASS SPECTROMETRY, INDUCTION, AND PROCESSING BY SRTA.
RC   STRAIN=ATCC BAA-679 / EGD-e;
RX   PubMed=16247833; DOI=10.1002/pmic.200402075;
RA   Pucciarelli M.G., Calvo E., Sabet C., Bierne H., Cossart P.,
RA   Garcia-del Portillo F.;
RT   "Identification of substrates of the Listeria monocytogenes sortases A and
RT   B by a non-gel proteomic analysis.";
RL   Proteomics 5:4808-4817(2005).
CC   -!- SUBCELLULAR LOCATION: Secreted, cell wall {ECO:0000255|PROSITE-
CC       ProRule:PRU00477, ECO:0000269|PubMed:11929538,
CC       ECO:0000269|PubMed:16247833}; Peptidoglycan-anchor
CC       {ECO:0000255|PROSITE-ProRule:PRU00477, ECO:0000269|PubMed:11929538,
CC       ECO:0000269|PubMed:16247833}.
CC   -!- INDUCTION: Present in both exponential and stationary phase (at protein
CC       level). {ECO:0000269|PubMed:16247833}.
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DR   EMBL; AL591984; CAD00927.1; -; Genomic_DNA.
DR   PIR; AI1413; AI1413.
DR   RefSeq; NP_466236.1; NC_003210.1.
DR   RefSeq; WP_003722074.1; NZ_CP023861.1.
DR   AlphaFoldDB; Q8Y3W5; -.
DR   SMR; Q8Y3W5; -.
DR   STRING; 169963.lmo2714; -.
DR   PaxDb; Q8Y3W5; -.
DR   EnsemblBacteria; CAD00927; CAD00927; CAD00927.
DR   GeneID; 987103; -.
DR   KEGG; lmo:lmo2714; -.
DR   PATRIC; fig|169963.11.peg.2780; -.
DR   eggNOG; ENOG5032Q7J; Bacteria.
DR   HOGENOM; CLU_890805_0_0_9; -.
DR   OMA; VEWIFVV; -.
DR   BioCyc; LMON169963:LMO2714-MON; -.
DR   Proteomes; UP000000817; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   InterPro; IPR019931; LPXTG_anchor.
DR   Pfam; PF00746; Gram_pos_anchor; 1.
PE   1: Evidence at protein level;
KW   Cell wall; Direct protein sequencing; Peptidoglycan-anchor;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255"
FT   CHAIN           27..315
FT                   /note="Cell wall protein Lmo2714"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_5004317025"
FT   PROPEP          287..315
FT                   /note="Removed by sortase A"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00477,
FT                   ECO:0000269|PubMed:11929538, ECO:0000305|PubMed:16247833"
FT                   /id="PRO_0000445904"
FT   REGION          27..76
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           283..287
FT                   /note="LPXTG sorting signal"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00477"
FT   COMPBIAS        27..44
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        45..60
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        61..76
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         286
FT                   /note="Pentaglycyl murein peptidoglycan amidated threonine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00477,
FT                   ECO:0000305|PubMed:11929538"
SQ   SEQUENCE   315 AA;  34669 MW;  17D3431EF7114D83 CRC64;
     MKKFHGLILT ALVTCLIIPF SLAASAETNE NGNNSTPTEE KTTDTTENII TEEKTEPAEP
     TKDTTVTPPQ KSKVQTTIDI TDSQEVYSYE QNSKIDLKDF TATLTDYTDT KLTNYRLAAN
     SKLSTAQTGI QEVTLLGDNE DGKTTAVKLN YLVKEKTAQL TITDMNFDLE TKIFTGKTKP
     FASVYMSSPA DENFGEGTTT ADKDGYFYAE WATTPKQITA YAFDESGNYS EEVTYQVPAK
     KQNEAVVTAP DKVKKIETKN AVKSATTKPT DVTKVTKDDK TDLPSTGDKG TEWIFVVAGV
     IVILVAVLLL RKRKK