ID   Y2725_STRCO             Reviewed;         285 AA.
AC   Q53936;
DT   05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=Putative lipoprotein SCO2725;
DE   Flags: Precursor;
GN   OrderedLocusNames=SCO2725; ORFNames=SCC46.10;
OS   Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces; Streptomyces albidoflavus group.
OX   NCBI_TaxID=100226;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=A3(2) / J802;
RX   PubMed=8550471; DOI=10.1128/jb.178.2.490-495.1996;
RA   Zhang Y.-X., Tang L., Hutchinson C.R.;
RT   "Cloning and characterization of a gene (msdA) encoding methylmalonic acid
RT   semialdehyde dehydrogenase from Streptomyces coelicolor.";
RL   J. Bacteriol. 178:490-495(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-471 / A3(2) / M145;
RX   PubMed=12000953; DOI=10.1038/417141a;
RA   Bentley S.D., Chater K.F., Cerdeno-Tarraga A.-M., Challis G.L.,
RA   Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA   Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA   Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.-H.,
RA   Kieser T., Larke L., Murphy L.D., Oliver K., O'Neil S., Rabbinowitsch E.,
RA   Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Saunders D.,
RA   Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA   Woodward J.R., Barrell B.G., Parkhill J., Hopwood D.A.;
RT   "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT   A3(2).";
RL   Nature 417:141-147(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000305}.
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DR   EMBL; L48550; AAA99191.1; -; Genomic_DNA.
DR   EMBL; AL939113; CAB75314.1; -; Genomic_DNA.
DR   RefSeq; NP_626958.1; NC_003888.3.
DR   RefSeq; WP_011028543.1; NZ_VNID01000020.1.
DR   AlphaFoldDB; Q53936; -.
DR   SMR; Q53936; -.
DR   GeneID; 1098159; -.
DR   KEGG; sco:SCO2725; -.
DR   PATRIC; fig|100226.15.peg.2781; -.
DR   HOGENOM; CLU_983222_0_0_11; -.
DR   OMA; MTASTEV; -.
DR   PhylomeDB; Q53936; -.
DR   Proteomes; UP000001973; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR029046; LolA/LolB/LppX.
DR   SUPFAM; SSF89392; SSF89392; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW   Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           23..285
FT                   /note="Putative lipoprotein SCO2725"
FT                   /id="PRO_0000248031"
FT   REGION          264..285
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   LIPID           23
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           23
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   285 AA;  29568 MW;  9296B19AE6964D79 CRC64;
     MKLKYTAAWV GLTAAAMVAA TACGSDGAKT AAGTADKAVD KGTAVMAALT RATDRTEELG
     SAEVRTTTEL DATGGEPISM DGTYSWGDGA AMDVEMDTAA AQMSALQDDP TTRVVMVDGA
     YFYDVDPQPN GPLAGKEWMR VDVAAVTGEA GADNMAANAD PTATLRYMTA STEVADLGEE
     TVLGRKTTHY RGSVGAEHVE RSKLTEAEKK AAIAALKASG GKLTCDIWVD GKDLPVRITQ
     TGAGMTVKMD FVKFGATKEI TAPPAAETGD LTEQVTKQRD AAIGQ