ID   Y2731_MYCS2             Reviewed;         454 AA.
AC   A0QVX6;
DT   22-JUL-2015, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Uncharacterized protein MSMEG_2731/MSMEI_2664;
GN   OrderedLocusNames=MSMEG_2731, MSMEI_2664;
OS   Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium
OS   smegmatis).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=246196;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700084 / mc(2)155;
RA   Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA   Fraser C.M.;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700084 / mc(2)155;
RX   PubMed=17295914; DOI=10.1186/gb-2007-8-2-r20;
RA   Deshayes C., Perrodou E., Gallien S., Euphrasie D., Schaeffer C.,
RA   Van-Dorsselaer A., Poch O., Lecompte O., Reyrat J.-M.;
RT   "Interrupted coding sequences in Mycobacterium smegmatis: authentic
RT   mutations or sequencing errors?";
RL   Genome Biol. 8:R20.1-R20.9(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700084 / mc(2)155;
RX   PubMed=18955433; DOI=10.1101/gr.081901.108;
RA   Gallien S., Perrodou E., Carapito C., Deshayes C., Reyrat J.-M.,
RA   Van Dorsselaer A., Poch O., Schaeffer C., Lecompte O.;
RT   "Ortho-proteogenomics: multiple proteomes investigation through orthology
RT   and a new MS-based protocol.";
RL   Genome Res. 19:128-135(2009).
RN   [4]
RP   INTERACTION WITH RIBOSOMAL PROTEIN S1, SUBUNIT, INDUCTION, DISRUPTION
RP   PHENOTYPE, AND NUCLEIC ACID-BINDING.
RX   PubMed=22590585; DOI=10.1371/journal.pone.0036666;
RA   Yang M., Chen Y., Zhou Y., Wang L., Zhang H., Bi L.J., Zhang X.E.;
RT   "MSMEG_2731, an uncharacterized nucleic acid binding protein from
RT   Mycobacterium smegmatis, physically interacts with RPS1.";
RL   PLoS ONE 7:E36666-E36666(2012).
CC   -!- SUBUNIT: Monomer. Binds ribosomal protein S1 (RpsA), RNA, ssDNA and
CC       dsDNA. {ECO:0000269|PubMed:22590585}.
CC   -!- INDUCTION: Constitutively expressed throughout the cell cycle (at
CC       protein level). {ECO:0000269|PubMed:22590585}.
CC   -!- DISRUPTION PHENOTYPE: No visible phenotype.
CC       {ECO:0000269|PubMed:22590585}.
CC   -!- MISCELLANEOUS: There are about 700 copies of the protein per cell
CC       during exponential growth. {ECO:0000269|PubMed:22590585}.
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DR   EMBL; CP000480; ABK72286.1; -; Genomic_DNA.
DR   EMBL; CP001663; AFP39132.1; -; Genomic_DNA.
DR   RefSeq; WP_011728548.1; NZ_SIJM01000032.1.
DR   RefSeq; YP_887064.1; NC_008596.1.
DR   AlphaFoldDB; A0QVX6; -.
DR   SMR; A0QVX6; -.
DR   STRING; 246196.MSMEI_2664; -.
DR   EnsemblBacteria; ABK72286; ABK72286; MSMEG_2731.
DR   EnsemblBacteria; AFP39132; AFP39132; MSMEI_2664.
DR   GeneID; 66734136; -.
DR   KEGG; msg:MSMEI_2664; -.
DR   KEGG; msm:MSMEG_2731; -.
DR   PATRIC; fig|246196.19.peg.2699; -.
DR   eggNOG; COG1196; Bacteria.
DR   OMA; DELWHRF; -.
DR   Proteomes; UP000000757; Chromosome.
DR   Proteomes; UP000006158; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR007139; DUF349.
DR   Pfam; PF03993; DUF349; 3.
PE   1: Evidence at protein level;
KW   DNA-binding; Reference proteome; RNA-binding.
FT   CHAIN           1..454
FT                   /note="Uncharacterized protein MSMEG_2731/MSMEI_2664"
FT                   /id="PRO_0000433595"
FT   REGION          1..60
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          390..454
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        22..42
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        390..434
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   454 AA;  49735 MW;  5B609086B8746320 CRC64;
     MRGPPRGVRG ADMTTSEPGG ATPKPTPRPT PHPTPRPVPR PSRVAPVVAA APSSDPHRFG
     RVDPDGTVWL ITGSGERVIG AWQAGDTESA FAHFGRRYDD LHTEVALLER RLATGTGDAR
     KIKSAAAALA ESLPTASVLG DVDALSARLS SILEQADEAA QNERAQRDEY RAAQTARKEA
     LAAEAEDIAA NSTQWKAAGD RLREILDEWR TITGLERKAD DALWKRYSAA RETFNRRRGS
     HFAELDRSRV SARQAKEELC ERAEALADST DWGATSAAFR DLLAEWKAAG RAAKDVDDAL
     WQRFKAAQDT FFSARNAAHA ERDAEFKANA AAKEALLAEA EKIDLSDNEA ARAALRVIGE
     KWDAIGKVPR ERAAELERRL RAIEKKIREA PTGGVDPEAK ARADQFRARA EQFERQAEKA
     EAAGRTKDAE EARASAAQWR QWAEAAAESL EKRR