ID   Y2732_MYCA1             Reviewed;         307 AA.
AC   A0QG83;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase MAV_2732;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MAV_2732;
OS   Mycobacterium avium (strain 104).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=243243;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=104;
RA   Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA   Fraser C.M.;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CP000479; ABK67525.1; -; Genomic_DNA.
DR   RefSeq; WP_011725007.1; NC_008595.1.
DR   AlphaFoldDB; A0QG83; -.
DR   SMR; A0QG83; -.
DR   EnsemblBacteria; ABK67525; ABK67525; MAV_2732.
DR   KEGG; mav:MAV_2732; -.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; ANGFEFP; -.
DR   OrthoDB; 847145at2; -.
DR   Proteomes; UP000001574; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..307
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase MAV_2732"
FT                   /id="PRO_0000361103"
FT   BINDING         133
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         162..163
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   307 AA;  34067 MW;  8083C9B4134248C3 CRC64;
     MSSTGSARTE GDSWDLASSV GATATMVAAS RALASRGPDP LLDDRFAEPL VRAVGHPFFV
     RMLDGQIPLD TDDMPMTLQQ RREQITVRTR FFDDFFRSAT AAGIRQAVIL AAGLDARAYR
     LSWPAGTVVF EVDQPEVISF KTDTLARLGA QPTAERRTVA VDLRDDWPTA LRDTGFDSSA
     RTAWIAEGLL PYLPPHAQDR LLDNITALSA PGSRLATENI TDMRVFTDER ARAMRSTWRQ
     HGLDIDVAEL VWLGERRPAG DHLEATGWSV TRLPTERVYA DYGFELPDNE ILREFRQAIS
     YLSAELG