ID   Y273_STRP6              Reviewed;         256 AA.
AC   Q5XDV5; P82552;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=Probable ABC transporter ATP-binding protein M6_Spy0273;
GN   OrderedLocusNames=M6_Spy0273;
OS   Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=286636;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-946 / MGAS10394;
RX   PubMed=15272401; DOI=10.1086/422697;
RA   Banks D.J., Porcella S.F., Barbian K.D., Beres S.B., Philips L.E.,
RA   Voyich J.M., DeLeo F.R., Martin J.M., Somerville G.A., Musser J.M.;
RT   "Progress toward characterization of the group A Streptococcus metagenome:
RT   complete genome sequence of a macrolide-resistant serotype M6 strain.";
RL   J. Infect. Dis. 190:727-738(2004).
RN   [2]
RP   PROTEIN SEQUENCE OF 17-42; 80-102; 110-118; 128-182 AND 207-235, AND MASS
RP   SPECTROMETRY.
RC   STRAIN=JRS4 / Serotype M6;
RA   Hogan D.A., Du P., Stevenson T.I., Whitton M., Kilby G.W., Rogers J.,
RA   VanBogelen R.A.;
RT   "Two-dimensional gel electrophoresis map of Streptococcus pyogenes
RT   proteins.";
RL   Submitted (MAY-2000) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Peripheral membrane
CC       protein {ECO:0000250}.
CC   -!- MASS SPECTROMETRY: Mass=28110.44; Method=Electrospray;
CC       Evidence={ECO:0000269|Ref.2};
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Ycf16 family.
CC       {ECO:0000305}.
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DR   EMBL; CP000003; AAT86408.1; -; Genomic_DNA.
DR   RefSeq; WP_002986023.1; NC_006086.1.
DR   AlphaFoldDB; Q5XDV5; -.
DR   SMR; Q5XDV5; -.
DR   EnsemblBacteria; AAT86408; AAT86408; M6_Spy0273.
DR   GeneID; 57852071; -.
DR   KEGG; spa:M6_Spy0273; -.
DR   HOGENOM; CLU_000604_48_1_9; -.
DR   OMA; MAMLEPK; -.
DR   Proteomes; UP000001167; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProt.
DR   CDD; cd03217; ABC_FeS_Assembly; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR010230; FeS-cluster_ATPase_SufC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR43204; PTHR43204; 1.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR01978; sufC; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   1: Evidence at protein level;
KW   ATP-binding; Cell membrane; Direct protein sequencing; Membrane;
KW   Nucleotide-binding; Transport.
FT   CHAIN           1..256
FT                   /note="Probable ABC transporter ATP-binding protein
FT                   M6_Spy0273"
FT                   /id="PRO_0000093214"
FT   DOMAIN          4..246
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         36..43
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   256 AA;  28110 MW;  0BE63689F9B4962B CRC64;
     MSILEINNLH VSIEGKEILK GVNLTLKTGE VAAIMGPNGT GKSTLSAAIM GNPNYEVTQG
     QILLDGVNIL DLEVDERARL GLFLAMQYPS EIPGITNAEF MRAAMNAGKA DEDKISVRDF
     ITKLDEKMAL LGMKEEMAER YLNEGFSGGE KKRNEILQLL MLEPKFALLD EIDSGLDIDA
     LKVVSKGVNE MRGKDFGAMI ITHYQRLLNY ITPDLVHVMM DGRIVLSGDA ALATRLEKEG
     YAGIAQDLGI EYKEES