ID   Y273_TREPA              Reviewed;         263 AA.
AC   O83297;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=Uncharacterized protein TP_0273;
GN   OrderedLocusNames=TP_0273;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AE000520; AAC65275.1; -; Genomic_DNA.
DR   PIR; D71342; D71342.
DR   RefSeq; WP_010881722.1; NC_021490.2.
DR   AlphaFoldDB; O83297; -.
DR   IntAct; O83297; 2.
DR   STRING; 243276.TPANIC_0273; -.
DR   EnsemblBacteria; AAC65275; AAC65275; TP_0273.
DR   GeneID; 57878817; -.
DR   KEGG; tpa:TP_0273; -.
DR   HOGENOM; CLU_1065349_0_0_12; -.
DR   OMA; FFDGWDN; -.
DR   OrthoDB; 1827826at2; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..263
FT                   /note="Uncharacterized protein TP_0273"
FT                   /id="PRO_0000202222"
FT   TRANSMEM        21..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        48..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        127..149
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        186..208
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   263 AA;  29742 MW;  9C40AF87E126E430 CRC64;
     MLPYAEVILF LIKKHCIDCG EAFFGIVVLN ALCLAGVGYS LLWHQGPGRS VLFVLVLATL
     YACLCAFCVV RGERGCDTLA DTNLRVFTHA LREVWLQSLW CALLQCVLFR TGKYVCTYYF
     ARTHSVFTAC GILSAWTYAL ACGALLWFVP VRARYRTHFR QCVYLSARVF FEHPCITFLM
     VLYSMGVLAL SVPMAFLFPG PCGIVLLWQD VLRTLCFRRA WLAAHEGRKA ACAPPIPWEQ
     LMCQMRAQSR AHTVGELFSP WKS