ID   Y2740_DICDI             Reviewed;         910 AA.
AC   Q54CQ8;
DT   24-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=von Willebrand factor A domain-containing protein DDB_G0292740;
GN   ORFNames=DDB_G0292740;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
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DR   EMBL; AAFI02000196; EAL61044.1; -; Genomic_DNA.
DR   RefSeq; XP_629483.1; XM_629481.1.
DR   AlphaFoldDB; Q54CQ8; -.
DR   SMR; Q54CQ8; -.
DR   PaxDb; Q54CQ8; -.
DR   EnsemblProtists; EAL61044; EAL61044; DDB_G0292740.
DR   GeneID; 8628873; -.
DR   KEGG; ddi:DDB_G0292740; -.
DR   dictyBase; DDB_G0292740; -.
DR   eggNOG; ENOG502QRPK; Eukaryota.
DR   HOGENOM; CLU_327738_0_0_1; -.
DR   InParanoid; Q54CQ8; -.
DR   OMA; FIRSNIY; -.
DR   PhylomeDB; Q54CQ8; -.
DR   PRO; PR:Q54CQ8; -.
DR   Proteomes; UP000002195; Chromosome 6.
DR   Gene3D; 3.40.50.410; -; 1.
DR   InterPro; IPR013694; VIT.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   Pfam; PF08487; VIT; 1.
DR   Pfam; PF13768; VWA_3; 1.
DR   SMART; SM00609; VIT; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; SSF53300; 1.
DR   PROSITE; PS51468; VIT; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..910
FT                   /note="von Willebrand factor A domain-containing protein
FT                   DDB_G0292740"
FT                   /id="PRO_0000389210"
FT   DOMAIN          63..194
FT                   /note="VIT"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00801"
FT   DOMAIN          346..515
FT                   /note="VWFA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00219"
FT   REGION          297..318
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          703..815
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        703..717
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        718..751
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        754..815
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   910 AA;  101823 MW;  8EE4EB7E947520B7 CRC64;
     MIKNLISAFS QGVGIQKKEL PSTIILNKDD YKEANYYNYY RNLELNKPDE VLARRIAGLA
     PIAYQYYNVS SFDNNQFKIV DFSIDSKLND TCLTCVWTQT YKNESKTPVE AVYRIPLSPL
     STVSAFSVQF NGKTLHGKIK DSTKAQEKYD DAIASGGQAF LAEKSKDDDN YFNFKLGNIP
     PTESSITIHI TMISEIGSHL NSLHYLLHRY CFPQSSNYNF SLSLSVNLSN SIKSIFFDGD
     KSHSLQYENK EKTKCIIQYK KSLGFNTQPN ILIVFELDDL NKPQSFIEKL SINKEDIKNN
     PHSDSDSDSD DEENKKENEK SSYAIALNFF PKFESINKED IYQKGEFIFL IDCSGSMSGN
     PIDSARRALE IIIRSLNEQC KFNIYCFGSG FNKAFQEGSR KYDDDSLAVV NRYVSNISAN
     LGGTELLQPI KDILSKEIDP EYPRQIFILT DGAVSDRSKL IEFVSKESKT TRIFTYGIGS
     SVDVELVVGL SKACKGYYTL IRNSSDMETE VMKLLSIAFE PTLSNVSFDW SQLLDLSNGK
     STTIIQSPTQ IRPIFNNERM MVYATIELDN DISNNIENHG QPVIVTMNAD GPLGDRLSYH
     VELDFKNYSQ SNSIHTLAAF KRIQDLEEIE RKSSKETEKL EIIKLGKKYN LVSKHTSLVV
     TSDSDSPTED TMKVINILPN NSQHPIIVDR CHTFAVNFNS PLQYQQQQQQ QQQNFNSGFA
     PPPPPMMSSG PPPPPGSSFG APPPPPPGGA FPTSSISEKK SSSQSSSSYL PPTMSLSRKS
     SLSPSSPSKN YPSPKLSSPS LSYGSTQSES TPSNDPLISL LAKQKANGSW SKSSIQDQFS
     SAISKIPNEL SAVEDVWATL LVISKIMKTF ASQKSKWELS VQKSNKWVKQ QLLKLNLSFD
     QFLELAKSNV