Y2742_MYCBO
ID Y2742_MYCBO Reviewed; 397 AA.
AC P0A615; A0A1R3Y202; O33228; X2BM35;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-MAR-2005, sequence version 1.
DT 25-MAY-2022, entry version 87.
DE RecName: Full=Uncharacterized membrane protein Mb2742;
GN OrderedLocusNames=BQ2027_MB2742;
OS Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=233413;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-935 / AF2122/97;
RX PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT "The complete genome sequence of Mycobacterium bovis.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC STRAIN=ATCC BAA-935 / AF2122/97;
RX PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA Robbe-Austerman S., Gordon S.V.;
RT "Updated reference genome sequence and annotation of Mycobacterium bovis
RT AF2122/97.";
RL Genome Announc. 5:E00157-E00157(2017).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the TerC family. {ECO:0000305}.
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DR EMBL; LT708304; SIU01360.1; -; Genomic_DNA.
DR RefSeq; NP_856388.1; NC_002945.3.
DR RefSeq; WP_003413979.1; NC_002945.4.
DR AlphaFoldDB; P0A615; -.
DR EnsemblBacteria; SIU01360; SIU01360; BQ2027_MB2742.
DR PATRIC; fig|233413.5.peg.3004; -.
DR OMA; EALHDNN; -.
DR Proteomes; UP000001419; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR005496; Integral_membrane_TerC.
DR InterPro; IPR022369; Integral_membrane_TerC_rswitch.
DR PANTHER; PTHR30238:SF0; PTHR30238:SF0; 1.
DR Pfam; PF03741; TerC; 1.
DR TIGRFAMs; TIGR03718; R_switched_Alx; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT CHAIN 1..397
FT /note="Uncharacterized membrane protein Mb2742"
FT /id="PRO_0000103420"
FT TRANSMEM 1..21
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 39..59
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 76..96
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 103..123
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 124..144
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 194..214
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 219..239
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 255..275
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 301..321
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 397 AA; 43679 MW; E85CCFDD414B4C3E CRC64;
MGASGLVWTL TIVLIAGLML VDYVLHVRKT HVPTLRQAVI QSATFVGIAI LFGIAVVVFG
GSELAVEYFA CYLTDEALSV DNLFVFLVII SSFGVPRLAQ QKVLLFGIAF ALVTRTGFIF
VGAALIENFN SAFYLFGLVL LVMAGNLARP TGLESRDAET LKRSVIIRLA DRFLRTSQDY
NGDRLFTVSN NKRMMTPLLL VMIAVGGTDI LFAFDSIPAL FGLTQNVYLV FAATAFSLLG
LRQLYFLIDG LLDRLVYLSY GLAVILGFIG VKLMLEALHD NKIPFINGGK PVPTVEVSTT
QSLTVIIIVL LITTAASFWS ARGRAQNAMA RARRYATAYL DLHYETESAE RDKIFTALLA
AERQINTLPT KYRMQPGQDD DLMTLLCRAH AARDAHM