ID   Y2742_VIBCH             Reviewed;         297 AA.
AC   Q9KNJ6;
DT   11-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=UPF0761 membrane protein VC_2742 {ECO:0000255|HAMAP-Rule:MF_00672};
GN   OrderedLocusNames=VC_2742;
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=243277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA   Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA   Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA   Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA   Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_00672}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_00672}.
CC   -!- SIMILARITY: Belongs to the UPF0761 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00672}.
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DR   EMBL; AE003852; AAF95881.1; -; Genomic_DNA.
DR   PIR; F82039; F82039.
DR   RefSeq; NP_232368.1; NC_002505.1.
DR   RefSeq; WP_001884068.1; NZ_LT906614.1.
DR   AlphaFoldDB; Q9KNJ6; -.
DR   STRING; 243277.VC_2742; -.
DR   DNASU; 2614905; -.
DR   EnsemblBacteria; AAF95881; AAF95881; VC_2742.
DR   GeneID; 57741333; -.
DR   KEGG; vch:VC_2742; -.
DR   PATRIC; fig|243277.26.peg.2617; -.
DR   eggNOG; COG1295; Bacteria.
DR   HOGENOM; CLU_032288_0_0_6; -.
DR   OMA; KQPKFRW; -.
DR   BioCyc; VCHO:VC2742-MON; -.
DR   Proteomes; UP000000584; Chromosome 1.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00672; UPF0761; 1.
DR   InterPro; IPR023679; UPF0761_bac.
DR   InterPro; IPR017039; Virul_fac_BrkB.
DR   PANTHER; PTHR30213; PTHR30213; 1.
DR   Pfam; PF03631; Virul_fac_BrkB; 1.
DR   PIRSF; PIRSF035875; RNase_BN; 1.
DR   TIGRFAMs; TIGR00765; yihY_not_rbn; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..297
FT                   /note="UPF0761 membrane protein VC_2742"
FT                   /id="PRO_0000200998"
FT   TRANSMEM        43..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
FT   TRANSMEM        100..120
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
FT   TRANSMEM        135..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
FT   TRANSMEM        181..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
FT   TRANSMEM        213..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
FT   TRANSMEM        245..265
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
SQ   SEQUENCE   297 AA;  33286 MW;  10BCF576215B8481 CRC64;
     MKLTHSFIKQ QARLGLNFFR YLLARMNHDR VNVNAGYLAY ITLLSMVPML TVLLSILSSF
     ALFANAGEVI QDFVITHFVP AAGEVVKTAL IEFVANTGKM TAVGGAFLFV AAIMLISNID
     KNLNYIWRVQ QKRRAVFSFS MYWMILTLGP ILVGASIAAT SYITSLKILD NEALSGVYNL
     FLRWLPFVLS YCAFVGLYLL VPNKKVHWQH AMLGALIAAI LFELSKKGFA AYITQFPSYQ
     LIYGALAAIP ILFVWVYLCW LIVLVGAEVT AALGEREHWS DSQDMLHFAP LPKNEKE