ID   Y275_HAEIN              Reviewed;         551 AA.
AC   P43975;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=Uncharacterized protein HI_0275;
GN   OrderedLocusNames=HI_0275;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; L42023; AAC21949.1; -; Genomic_DNA.
DR   PIR; B64005; B64005.
DR   RefSeq; NP_438444.1; NC_000907.1.
DR   RefSeq; WP_005694030.1; NC_000907.1.
DR   AlphaFoldDB; P43975; -.
DR   SMR; P43975; -.
DR   STRING; 71421.HI_0275; -.
DR   PRIDE; P43975; -.
DR   EnsemblBacteria; AAC21949; AAC21949; HI_0275.
DR   KEGG; hin:HI_0275; -.
DR   PATRIC; fig|71421.8.peg.290; -.
DR   eggNOG; COG1368; Bacteria.
DR   HOGENOM; CLU_036702_0_0_6; -.
DR   OMA; LIQYDIT; -.
DR   PhylomeDB; P43975; -.
DR   BioCyc; HINF71421:G1GJ1-295-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008484; F:sulfuric ester hydrolase activity; IEA:InterPro.
DR   GO; GO:0016740; F:transferase activity; IMP:BHF-UCL.
DR   GO; GO:0009244; P:lipopolysaccharide core region biosynthetic process; IMP:BHF-UCL.
DR   Gene3D; 3.40.720.10; -; 1.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR000917; Sulfatase_N.
DR   Pfam; PF00884; Sulfatase; 1.
DR   SUPFAM; SSF53649; SSF53649; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..551
FT                   /note="Uncharacterized protein HI_0275"
FT                   /id="PRO_0000077904"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        25..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        99..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        124..144
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        266..286
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        490..510
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   551 AA;  62257 MW;  BF08FE215695D610 CRC64;
     MIAYIFLALF TIAAVIFIVN SHYRWTYFFA ITLFTFLFGG MLMVSSQWQR ALNFSSVLFV
     VLMLFHRLKI HYYKQPLLIS DFFLVVDWRN WETLIHYKGA LFGVIGLLAL LGYAIFGFND
     VESLGVLGNS IGALLFIVSF SLMWHYSKNP SAVQVWLDSL PDDGRDVFLN LPMSCRGIFF
     KVPNFDGNSQ NFIEKMTALS SDANNLSETK PDIVVTLMES TLNPHQFAFS QQSIPPLSMF
     EPQNDTVFAS PLRVHTFAGA TWKSEFAFLA GVPSTDFGAL ASGVFYSVVP HLQSGLVKNL
     KAQGYFCVAL SPFTKGNYNA KSAYDHFGFD LMLQPQDLGY PAPISKNLWD ISSEEMMKYT
     RMILEKQHPA LENVDQPMFV YVLTMREHGP YELGMENTFN LQMPNLGAKS ISALNDYTQR
     IVALNDAIEG INNYLHERKK PFVLGYFGDH QVAFDNAIPP KKGDYAQPDY VTQFVVRSNC
     ASQFKQEQKF LDLAFAGGVL MNVAGLSAED EFMKANMAMC KLSDGKLEDS SDIQLLNNYR
     HYLYQTLAIA R