ID   Y2766_STAAR             Reviewed;         570 AA.
AC   Q6GDC0;
DT   21-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=Putative ABC transporter ATP-binding protein SAR2766;
DE            EC=7.-.-.-;
GN   OrderedLocusNames=SAR2766;
OS   Staphylococcus aureus (strain MRSA252).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=282458;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MRSA252;
RX   PubMed=15213324; DOI=10.1073/pnas.0402521101;
RA   Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J.,
RA   Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A.,
RA   Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C.,
RA   Clark L., Corton C., Cronin A., Doggett J., Dowd L., Feltwell T., Hance Z.,
RA   Harris B., Hauser H., Holroyd S., Jagels K., James K.D., Lennard N.,
RA   Line A., Mayes R., Moule S., Mungall K., Ormond D., Quail M.A.,
RA   Rabbinowitsch E., Rutherford K.M., Sanders M., Sharp S., Simmonds M.,
RA   Stevens K., Whitehead S., Barrell B.G., Spratt B.G., Parkhill J.;
RT   "Complete genomes of two clinical Staphylococcus aureus strains: evidence
RT   for the rapid evolution of virulence and drug resistance.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004).
CC   -!- FUNCTION: Probably part of an ABC transporter complex. Responsible for
CC       energy coupling to the transport system (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Peripheral membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR   EMBL; BX571856; CAG41741.1; -; Genomic_DNA.
DR   RefSeq; WP_000138663.1; NC_002952.2.
DR   AlphaFoldDB; Q6GDC0; -.
DR   SMR; Q6GDC0; -.
DR   KEGG; sar:SAR2766; -.
DR   HOGENOM; CLU_000604_86_7_9; -.
DR   OMA; DPMTRLD; -.
DR   OrthoDB; 870493at2; -.
DR   Proteomes; UP000000596; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProt.
DR   CDD; cd03225; ABC_cobalt_CbiO_domain1; 2.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR022216; ABC_Co_transporter.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR015856; ABC_transpr_CbiO/EcfA_su.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 2.
DR   Pfam; PF12558; DUF3744; 1.
DR   SMART; SM00382; AAA; 2.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding; Repeat;
KW   Translocase; Transport.
FT   CHAIN           1..570
FT                   /note="Putative ABC transporter ATP-binding protein
FT                   SAR2766"
FT                   /id="PRO_0000092073"
FT   DOMAIN          6..247
FT                   /note="ABC transporter 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   DOMAIN          304..537
FT                   /note="ABC transporter 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         40..47
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         338..345
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   570 AA;  64206 MW;  EBC0DB7E9E37F619 CRC64;
     MTEPIISFKD FSFQYHSQAT PTLQNINVDI YPGEKVLVVG ASGSGKSTFA NCINGLIPFK
     TKGNVTGELH INNQDATVSC LHKRSNVVGT VLQDTDGQFI GLTAAEDMAF LLENNCVEQD
     DMKKNVSYWA EKVDMIEHLN HRPQDLSGGQ KQRVSLGGIL IHRTPILILD EPLANLDPAT
     GHETLRLLNN IHEETKSTMI IVEHRLEESL DDTFDRVLLF KDGKIIANTT PSDLLKSSKL
     KEAGIREPLY CTALKYAEVD VESIDNLANL REVCMSEHVK FKVKKWIDKT SSNDDNKYKS
     EPLLELNEVC VQYSDYSNSV LNNVQLNVYR REMLSIVGHN GAGKSTLAKA ICGFLDITGN
     IQFCNKGFNQ LSISERSEFI GYVMQNPNHM ISEKMIYDEV ALGLRARGMK ESDIKIRVEN
     VLKICGLYAF RNWPIAALSY GQKKRVTIAS VLVLNPEIII LDEPTAGQDF YHYNEIMSFL
     IELNRQGKTI IMITHDMHLL SEYSSRTVVL SKGQVVADTT PVLVLNDKKI CEIASLRQTS
     LFEMAEYIGI SEPQKLIQLF INHDRKVRRQ