ID   Y2771_STRCO             Reviewed;         262 AA.
AC   Q9L082;
DT   08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Phosphatase SCO2771;
DE            EC=3.1.3.- {ECO:0000305|PubMed:17851715};
GN   OrderedLocusNames=SCO2771; ORFNames=SCC105.02;
OS   Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces; Streptomyces albidoflavus group.
OX   NCBI_TaxID=100226;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-471 / A3(2) / M145;
RX   PubMed=12000953; DOI=10.1038/417141a;
RA   Bentley S.D., Chater K.F., Cerdeno-Tarraga A.-M., Challis G.L.,
RA   Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA   Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA   Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.-H.,
RA   Kieser T., Larke L., Murphy L.D., Oliver K., O'Neil S., Rabbinowitsch E.,
RA   Rajandream M.A., Rutherford K.M., Rutter S., Seeger K., Saunders D.,
RA   Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA   Woodward J.R., Barrell B.G., Parkhill J., Hopwood D.A.;
RT   "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT   A3(2).";
RL   Nature 417:141-147(2002).
RN   [2]
RP   FUNCTION AS A PHOSPHATASE, AND DISRUPTION PHENOTYPE.
RC   STRAIN=ATCC BAA-471 / A3(2) / M145;
RX   PubMed=17851715; DOI=10.1007/s00284-007-9014-7;
RA   Marineo S., Cusimano M.G., Limauro D., Coticchio G., Puglia A.M.;
RT   "The histidinol phosphate phosphatase involved in histidine biosynthetic
RT   pathway is encoded by SCO5208 (hisN) in Streptomyces coelicolor A3(2).";
RL   Curr. Microbiol. 56:6-13(2008).
CC   -!- FUNCTION: Displays phosphatase activity against p-nitrophenyl phosphate
CC       (pNPP) in vitro; however, the physiological substrate is unknown.
CC       {ECO:0000269|PubMed:17851715}.
CC   -!- DISRUPTION PHENOTYPE: Disruption of this gene does not cause histidine
CC       auxotrophy. {ECO:0000269|PubMed:17851715}.
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DR   EMBL; AL939113; CAB87208.1; -; Genomic_DNA.
DR   RefSeq; NP_627001.1; NC_003888.3.
DR   RefSeq; WP_003976029.1; NZ_VNID01000010.1.
DR   AlphaFoldDB; Q9L082; -.
DR   STRING; 100226.SCO2771; -.
DR   GeneID; 1098205; -.
DR   KEGG; sco:SCO2771; -.
DR   PATRIC; fig|100226.15.peg.2828; -.
DR   eggNOG; ENOG50335IE; Bacteria.
DR   HOGENOM; CLU_092811_0_0_11; -.
DR   OMA; ADHGWAG; -.
DR   Proteomes; UP000001973; Chromosome.
DR   GO; GO:0016791; F:phosphatase activity; IDA:UniProtKB.
DR   InterPro; IPR031423; Phosphatase_SCO2771.
DR   Pfam; PF15698; Phosphatase; 1.
PE   1: Evidence at protein level;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..262
FT                   /note="Phosphatase SCO2771"
FT                   /id="PRO_0000404326"
SQ   SEQUENCE   262 AA;  28390 MW;  19B63CC7E5082699 CRC64;
     MPIPGTPSRA ELAEHLVRTR IAGDVATPRE NNLSHYRKLA NGDRGFWLGL ELGDRWSDEQ
     DVLAVMAERV GVNDDPEHRY GQDTIDPELT ISALERMAGR LRKAADGGQR VLFATGHPGG
     LLDVHRATAA ALRDAGCEIV VIPEGLTTEE GYVQQFADVS VLEHGASLWH THSGEPMKAI
     LTGLEREGRP LPDLVVADHG WAGYAAQHGV DSVGYADCND PALFLAESEG TLQVAVPLDD
     HVVSPRYYDP MTAYLLTEAG LK