ID   Y2778_STAA8             Reviewed;         231 AA.
AC   Q2FVD5;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Uncharacterized oxidoreductase SAOUHSC_02778;
DE            EC=1.-.-.-;
GN   OrderedLocusNames=SAOUHSC_02778;
OS   Staphylococcus aureus (strain NCTC 8325 / PS 47).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=93061;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC 8325 / PS 47;
RA   Gillaspy A.F., Worrell V., Orvis J., Roe B.A., Dyer D.W., Iandolo J.J.;
RT   "The Staphylococcus aureus NCTC 8325 genome.";
RL   (In) Fischetti V., Novick R., Ferretti J., Portnoy D., Rood J. (eds.);
RL   Gram positive pathogens, 2nd edition, pp.381-412, ASM Press, Washington
RL   D.C. (2006).
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000305}.
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DR   EMBL; CP000253; ABD31782.1; -; Genomic_DNA.
DR   RefSeq; WP_000217466.1; NZ_LS483365.1.
DR   RefSeq; YP_501238.1; NC_007795.1.
DR   AlphaFoldDB; Q2FVD5; -.
DR   SMR; Q2FVD5; -.
DR   STRING; 1280.SAXN108_2731; -.
DR   EnsemblBacteria; ABD31782; ABD31782; SAOUHSC_02778.
DR   GeneID; 3921433; -.
DR   KEGG; sao:SAOUHSC_02778; -.
DR   PATRIC; fig|93061.5.peg.2513; -.
DR   eggNOG; COG4221; Bacteria.
DR   HOGENOM; CLU_010194_2_10_9; -.
DR   OMA; ITGGRNW; -.
DR   PRO; PR:Q2FVD5; -.
DR   Proteomes; UP000008816; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR002347; SDR_fam.
DR   Pfam; PF00106; adh_short; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase; Reference proteome.
FT   CHAIN           1..231
FT                   /note="Uncharacterized oxidoreductase SAOUHSC_02778"
FT                   /id="PRO_0000300476"
FT   ACT_SITE        153
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000250"
FT   BINDING         10..34
FT                   /ligand="NADP(+)"
FT                   /ligand_id="ChEBI:CHEBI:58349"
FT                   /evidence="ECO:0000250"
FT   BINDING         140
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   231 AA;  24604 MW;  189774147ABD5C69 CRC64;
     MTVLTDKVAV VTGAGSGIGE AIATLLHEEG AKVVLAGRNK EKLQNVANQL SQDSVKVVPT
     DVTNKEEVDE LIKIAQQTFG GLDIVINSAG QMLSSKITDY QVDEWDSMID VNIKGTLYTA
     QAALPTMLEQ SSGHLINIAS ISGFEVTKSS TIYSATKAAV HTITQGLEKE LAKTGVKVTS
     ISPGMVDTAI TAAYNPTDRK KLEPQDIAEA VLYALTQPKH VNVNEITVRP V